zinquin

zinquin is an ethyl ester in second source; specific chelator for zinc(II)

Also Known As:

(2-methyl-8-p-toluenesulfonamido-6-quinolyloxy)acetic acid; ethyl (2-methyl-8-p-toluenesulfonamido-6-quinolyloxy)acetate; Acetic acid, ((2-methyl-8-(((4-methylphenyl)sulfonyl)amino)-6-quinolinyl)oxy)-

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Toluene: 931
        Tosyl Compounds
        zinquin: 6
- Sulfur Compounds: 278
  - Sulfones: 534
    - Tosyl Compounds
      - zinquin: 6
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        zinquin: 6

Experts

1.	Kong, Jilie: 1 article (08/2016)
2.	Li, Yong: 1 article (08/2016)
3.	Qingguang, Ren: 1 article (08/2016)
4.	Song, Wenshuang: 1 article (08/2016)
5.	Sun, Yang: 1 article (08/2016)
6.	Tang, Xiaoling: 1 article (08/2016)
7.	Bagasra, Omar: 1 article (08/2011)
8.	Costello, Leslie C: 1 article (08/2011)
9.	Desouki, Mohamed M: 1 article (08/2011)
10.	Franklin, Renty B: 1 article (08/2011)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2016 - "In this work, the authors have selected zinquin ethyl ester, a Zn(2+)-specific fluorescent molecular probe, to efficiently differentiate ZnO NPs and Zn(2+), and combined with confocal laser scanning microscopy (CLSM) to in situ study the Zn(2+) release process of ZnO NPs in cancer cell system through detecting the change of Zn(2+) level over time. "
2.	Ischemia 09/01/2006 - "The rats were sacrificed 4-24 h after retinal ischemia by high intra-ocular pressure, and the retinas were prepared for microscopic examination of retinal cell degeneration, and fluorescence microscopy using zinquin ethyl ester as the zinc ion-specific probe. " 09/01/1997 - "Zn2+ was shown to accumulate in CA1 pyramidal neurons expressing ZnT-1 mRNA after the ischemia by using zinquin, a zinc-specific fluorescent dye. "
3.	Lymphoma (Lymphomas) 08/01/2002 - "Reactive changes in free intracellular zinc cation concentration ([Zn(2+)](i)) were monitored, using the fluorescent probe Zinquin, in human lymphoma cells exposed to the DNA-damaging agent VP-16. "
4.	Glioma (Gliomas) 09/01/2004 - "Administration of the NO donor S-nitrosocysteine (SNOC) caused a rapid drop in the fluorescence of the zinc-specific fluorescence of the zinc probe zinquin in C6 glioma cells. "
5.	Adenocarcinoma 08/15/2011 - "With in situ Dithizone and Zinquin staining of normal pancreas and adenocarcinoma tissue sections, we show for the first time, a consistent major loss of zinc in ductal and acinar epithelium in adenocarcinoma compared to the normal epithelium. "

Related Drugs and Biologics

1.	Esters
2.	Molecular Probes (Molecular Probe)
3.	Zinc
4.	Fluorescent Dyes (Fluorescent Probes)
5.	Messenger RNA (mRNA)
6.	Retinaldehyde (Retinal)
7.	Etoposide (VP 16)
8.	DNA (Deoxyribonucleic Acid)
9.	Dithizone
10.	Cations

Related Therapies and Procedures

1.	Lasers (Laser)