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SF 6,5

structure given in first source; an Arg-Gly-Asp mimetic; inhibits adhesive interactions between tumor cells and Arg-Gly-Arg (RGD)

Also Known As:

SF-6,5

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Valerates: 135
      - SF 6,5: 3
- Amidines: 14
  - Guanidines: 29
    - SF 6,5: 3
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Valerates: 135
      - SF 6,5: 3

Experts

1.	Aeed, H: 1 article (07/2000)
2.	Bruck, R: 1 article (07/2000)
3.	Halpern, Z: 1 article (07/2000)
4.	Hershkoviz, R: 1 article (07/2000)
5.	Lider, O: 1 article (07/2000)
6.	Shirin, H: 1 article (07/2000)

Related Diseases

1.	Liver Cirrhosis (Hepatic Cirrhosis) 07/01/2000 - "In rats, the progression of thioacetamide-induced liver cirrhosis was markedly inhibited by the co-administration of the RGD mimetic SF-6,5. " 07/01/1997 - "In rats, the progression of thioacetamide-induced liver cirrhosis was markedly inhibited by the coadministration of the RGD mimetic SF-6,5. "
2.	Neoplasms (Cancer) 12/02/1993 - "Moreover, SF-6,5 could prevent mouse death caused by massive colonization of tumor cells in the lungs. "
3.	Neoplasm Metastasis (Metastasis) 12/02/1993 - "Daily administration in vivo of SF-6,5 to mice inhibited the formation of B16-F10 colonies in experimental and spontaneous models of metastases. "
4.	Melanoma (Melanoma, Malignant) 12/02/1993 - "RGD-containing peptides and the RGD mimetic, compound SF-6,5, but not the Arg-Gly-Glu (RGE) peptide or the corresponding mimetic, specifically inhibited B16-F10 melanoma cell adhesion to immobilized VN and FN. "

Related Drugs and Biologics

1.	Thioacetamide (Thioacetamid)
2.	Peptides (Polypeptides)
3.	arginyl-glycyl-glutamic acid