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butaperazine
was heading 1964-94 (Prov 1964-73); use PHENOTHIAZINES to search BUTAPERAZINE 1966-94
Also Known As:
butyrylperazine; 1-Butanone, 1-(10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazin-2-yl)-
Networked:
12
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Phenothiazines: 506
butaperazine: 12
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Phenothiazines: 506
butaperazine: 12
Related Diseases
1.
Schizophrenia (Dementia Praecox)
11/01/1968 - "
Evaluation of butaperazine in chronic schizophrenia.
"
12/01/1970 - "
Relative efficacy of butaperazine and chlorpromazine in acute schizophrenia.
"
07/01/1970 - "
[Comparative study of butaperazine and prochlorperazine for schizophrenia in acute phase].
"
02/01/1965 - "
[COMPARATIVE STUDY OF BUTAPERAZINE AND PROCHLORPERAZINE IN CHRONIC SCHIZOPHRENIA].
"
2.
Alzheimer Disease (Alzheimer's Disease)
02/18/1967 - "
A controlled trial of butyrylperazine ("Randolectil") in senile dementia.
"
3.
Catalepsy
01/01/1980 - "
The action of butaperazine was diminished and simultaneously prolonged by fluorination in the position 3 or 7 as evidenced by a number of tests (prolongation of the resting time, catalepsy, apomorphine and dexphenmetrazine antagonism, conditioned escape reflex, aggressivity, algesimetry) on the rat and the mouse.
"
07/01/1991 - "
The ED50, namely the doses after which the resting time increases by 50% during the first 10 min of the exploration phase of mice has been determined of diazepam, chlordiazepoxide, haloperidol, droperidol, fluphenazine, butaperazine, 7-fluorobutaperazine, and chlorpromazine and it was compared with the ED 50 determined in the contact bottom plates motimeter according to Knoll et al. in mice and in the catalepsy test according to Wirth et al. in rats.
"
4.
Tardive Dyskinesia
04/01/1985 - "
Butaperazine pharmacokinetics in tardive dyskinesia.
"
08/01/1988 - "
Administration of butaperazine and plasma methionine-enkephalin levels in schizophrenic and affective disorder patients with tardive dyskinesia.
"
5.
Mood Disorders (Mood Disorder)
08/01/1988 - "
Administration of butaperazine resulted in significant changes (increases) of neuropeptide plasma concentration only in the affective disorder with TD subgroup, reaching statistical significance over their own baseline at 8, 10.5, and 24 hours, and at baseline (0 hr), 8-, and 48-hour intervals when compared with the affective disorder patients without TD.
"
08/01/1988 - "
Administration of butaperazine and plasma methionine-enkephalin levels in schizophrenic and affective disorder patients with tardive dyskinesia.
"
Related Drugs and Biologics
1.
Chlorpromazine (Thorazine)
2.
Prochlorperazine (Compazine)
3.
Neuropeptides
4.
Haloperidol (Haldol)
5.
Fluphenazine (Prolixin)
6.
Methionine Enkephalin
7.
Droperidol
8.
Diazepam (Valium)
9.
Chlordiazepoxide (Elenium)
10.
Apomorphine
Related Therapies and Procedures
1.
Therapeutics