oxypertine

was heading 1975-94 (see under INDOLES 1975-90); use PIPERAZINES to search OXYPERTINE 1975-94; antipsychotic agent also used in severe depression; it has potentially dangerous side effects

Also Known As:

Networked: 35 relevant articles (1 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bergman, Hanna: 1 article (01/2018)
2.	El-Sayeh, Hany G: 1 article (01/2018)
3.	Rathbone, John: 1 article (01/2018)
4.	Soares-Weiser, Karla: 1 article (01/2018)

Related Diseases

1.	Tardive Dyskinesia 11/01/1986 - "A 6-month, double-blind, placebo-controlled study of oxypertine in tardive dyskinesia is described. " 11/01/1986 - "Oxypertine in tardive dyskinesia: a long-term controlled study." 01/01/1984 - "Oxypertine in tardive dyskinesia: an 8-week controlled study." 01/01/1980 - "A study was undertaken to investigate the effects of oxypertine in treating tardive dyskinesia. " 01/01/1980 - "A controlled trial of oxypertine in tardive dyskinesia."
2.	Schizophrenia (Dementia Praecox) 10/01/1967 - "An extended trial of oxypertine in five selected cases of chronic schizophrenia." 07/01/1968 - "[Our experience with oxypertine in chronic schizophrenia]." 11/01/1967 - "Oxypertine in the treatment of schizophrenia." 01/01/1970 - "[Results of oxypertine therapy of chronic schizophrenia]." 01/01/1984 - "In a double-blind placebo controlled trial of oxypertine in the treatment of tardive dyskinesia, 33 patients with chronic schizophrenia received either oxypertine or placebo. "
3.	Psychotic Disorders (Schizoaffective Disorder) 03/01/1971 - "[Clinical study of oxypertine in chronic schizophrenic psychoses]." 10/03/1968 - "Oxypertine in schizophrenic psychoses. " 12/01/1969 - "A comparative trial of oxypertine and chlorpromazine in the treatment of acute psychoses." 08/01/1974 - "A controlled comparison of oxypertine and perphenazine in schizophrenic psychoses." 05/01/1975 - "In chronic psychotic disorders with inertia, oxypertine thus seems to be a neuroleptic which is strong enough to prevent exacerbation of delusions and hallucinations while at the same time increasing the level of motivation. "
4.	Catalepsy 01/01/1992 - "Although acute treatment with haloperidol or oxypertine induced catalepsy, tolerance to catalepsy developed following chronic treatment with haloperidol but not with oxypertine. " 04/01/1983 - "The indole analogues were shown to antagonize amphetamine-induced toxicity in aggregated mice, to indicate a 'tranquillizing' action but, in contrast to haloperidol and oxypertine, showed weak or no activity in other classical behavioural tests for neuroleptic action, catalepsy induction and stereotypy antagonism. "
5.	Parkinsonian Disorders (Parkinsonism) 02/01/1970 - "In producing hypothermia and sedation, the three compounds were equiactive.3. Oxypertine, another drug apt to produce Parkinsonism in man, caused a severe reduction in striatal DA and hypothalamic noradrenaline (NA). " 02/01/1970 - "Possible modes of action of atropine are discussed.7. At present we know of two types of biochemical changes which may occur in the brain of animals after treatment with drugs apt to cause Parkinsonism in man: a loss of cerebral catecholamines, as seen after reserpine or oxypertine, or an increase in turnover of DA as after phenothiazines and butyrophenones."

Related Drugs and Biologics

1.	Methoxyhydroxyphenylglycol
2.	Chlorpromazine (Thorazine)
3.	Haloperidol (Haldol)
4.	Reserpine (Serpasil)
5.	Therapeutic Uses
6.	Tiapride Hydrochloride
7.	Celiprolol (ST1396)
8.	Dopamine Agents (Dopaminergic Agents)
9.	Thioridazine (Mellaril)
10.	Tetrabenazine (Nitoman)

Related Therapies and Procedures

1.	Therapeutics
2.	Aftercare (After-Treatment)