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farnesal

Also Known As:

3,7,11-trimethyldodeca-2,6,10-trienal; 2,6,10-Dodecatrienal, 3,7,11-trimethyl-

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Farnesol: 162
        farnesal: 6
- Alcohols: 595
  - Fatty Alcohols: 172
    - Farnesol: 162
      - farnesal: 6
Lipids: 114793
- Fatty Alcohols: 172
  - Farnesol: 162
    - farnesal: 6

Experts

1.	Li, Haonan: 2 articles (12/2014 - 05/2012)
2.	Liao, Jie: 2 articles (12/2014 - 05/2012)
3.	Yang, Guang-Yu: 2 articles (12/2014 - 05/2012)
4.	Zhang, Wanying: 2 articles (12/2014 - 05/2012)
5.	Chen, Lin: 1 article (06/2020)
6.	Chen, Zhenyu: 1 article (06/2020)
7.	Li, Ting: 1 article (06/2020)
8.	Lin, Yan: 1 article (06/2020)
9.	Luo, Zhongling: 1 article (06/2020)
10.	Wang, Lujun: 1 article (06/2020)

Related Diseases

1.	Neoplasms (Cancer) 04/27/2012 - "Molecular docking and site-directed mutagenesis studies suggested that the nonconserved residues Ser118, Met120, and Phe311 in AKR1C3 are important for determining the inhibitory potency and selectivity of 1. The AKR1C3-mediated metabolism of 17-ketosteroid and farnesal in cancer cells was inhibited by 1, which was effective from 0.2 μM with an IC(50) value of about 30 μM. "
2.	Type 2 Diabetes Mellitus (MODY) 11/06/2019 - "Twelve terpenoids were evaluated in the treatment of type 2 diabetes mellitus: seven monoterpenes (geranyl acetate (1), geranic acid (2), citral (3), geraniol (4), methyl geranate (5), nerol (6), and citronellic acid (7)), three sesquiterpenes (farnesal (8), farnesol (9), and farnesyl acetate (10)), one diterpene (geranylgeraniol (11)), and one triterpene (squalene (12)) were selected to carry out a study on normoglycemic and streptozotocin-induced diabetic mice. "
3.	Carcinogenesis 12/28/2014 - "Metabolizing these lipid substrates appears crucial to carcinogenesis, particularly for farnesal/geranylgeranial that involves protein prenylation. " 05/01/2012 - "Aldo-keto reductase family 1B10 (AKR1B10) exhibits more restricted lipid substrate specificity (including farnesal, geranylgeranial, retinal and carbonyls), and metabolizing these lipid substrates has a crucial role in promoting carcinogenesis. "
4.	Necrosis 10/01/1976 - "Employing an in vitro maintenance system, in which 8-day-old Hymenolepis diminuta survives for 24 hr (Fioravanti and MacInnis, 1976), it was found that farnesol or farnesal supplementation of the medium had no beneficial effects on maintenance and these substances induced necrosis at higher concentrations. "
5.	Dental Caries (Decay, Dental) 06/11/2020 - "Farnesal-loaded pH-sensitive polymeric micelles provided effective prevention and treatment on dental caries."

Related Drugs and Biologics

1.	Farnesol
2.	Monoterpenes (Monoterpenoids)
3.	Triterpenes
4.	Terpenes (Terpenoids)
5.	Streptozocin (Streptozotocin)
6.	Squalene
7.	Sesquiterpenes
8.	Diterpenes
9.	citronellic acid
10.	geranyl acetate