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Clara cell antigen
found in bronchioloalveolar carcinoma of Syrian hamsters; aa sequence has been determined
Networked:
9
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Neoplasm Proteins: 2
Clara cell antigen: 9
Experts
1.
Fedorov, Lev M
: 1 article (05/2003)
2.
Götz, Rudolf
: 1 article (05/2003)
3.
Papadopoulos, Thomas
: 1 article (05/2003)
4.
Rapp, Ulf R
: 1 article (05/2003)
5.
Twardzik, Thomas
: 1 article (05/2003)
6.
Tyrsin, Oleg Y
: 1 article (05/2003)
Related Diseases
1.
Neoplasms (Cancer)
08/01/1991 - "
In several mice from both groups, hyperplasias and tumors were composed of cells expressing Clara cell antigen.
"
09/01/1995 - "
One-half of all tumors were positive for the Clara cell antigen CC10 and 21% of NNK-induced tumors were mucin positive, compared with 2% of NNK/O2-induced tumors (P = 0.003).
"
01/01/1989 - "
Immunohistochemical demonstration of Clara cell antigen in lung tumors of bronchiolar origin induced by N-nitrosodiethylamine in Syrian golden hamsters.
"
06/01/1985 - "
Rat Clara cell antigen was found, however, only focally within one adenoma induced by N-nitrosomethylurea and one adenoma in a hyperplastic lesion, and also focally in three neoplasms which occurred naturally.
"
05/01/2003 - "
Coexpression of lung epithelial cell markers surfactant protein C and Clara cell antigen suggests that tumor cell dedifferentiation could be involved in this process.
"
2.
Hyperplasia
08/01/1991 - "
In several mice from both groups, hyperplasias and tumors were composed of cells expressing Clara cell antigen.
"
01/01/1989 - "
Therefore, chemically induced bronchiolar hyperplasias and pulmonary neoplasms of Syrian golden hamsters were analyzed by avidin-biotin immunohistochemistry to localize a hamster-specific Clara cell antigen (CCA) and keratin.
"
03/01/1985 - "
The localization of surfactant apoprotein (SAP) and the Clara cell antigen(s) (CCA) was studied in naturally occurring and experimentally induced pulmonary hyperplasias and neoplasms by avidin-biotin peroxidase complex (ABC) immunocytochemistry.
"
3.
Lung Neoplasms (Lung Cancer)
03/01/1985 - "
Immunocytochemical localization of the surfactant apoprotein and Clara cell antigen in chemically induced and naturally occurring pulmonary neoplasms of mice.
"
01/01/1989 - "
Therefore, chemically induced bronchiolar hyperplasias and pulmonary neoplasms of Syrian golden hamsters were analyzed by avidin-biotin immunohistochemistry to localize a hamster-specific Clara cell antigen (CCA) and keratin.
"
4.
Benign Fibrous Histiocytoma (Dermatofibroma)
08/01/1988 - "
Using a panel of various antibodies on eight cases, the authors found that sclerosing hemangiomas expressed cytokeratin (seven cases), epithelial membrane antigen (seven cases), carcinoembryonic antigen (five cases), vimentin (seven cases), surfactant apoprotein (eight cases), and Clara cell antigen (five cases).
"
5.
Adenosquamous Carcinoma
05/01/1994 - "
With the exception of one adenosquamous carcinoma, Clara cell antigen immunostaining was not detected in any of the pulmonary lesions but was detected in nonciliated cuboidal epithelial (Clara) cells in normal bronchioles.
"
Related Drugs and Biologics
1.
Surface-Active Agents (Surfactants)
2.
Biotin (Vitamin H)
3.
Avidin
4.
Apoproteins
5.
Keratins (Keratin)
6.
Antibodies
7.
Mucin-1 (CA 15-3 Antigen)
8.
Vimentin
9.
Protein C
10.
Peroxidase (Myeloperoxidase)