FLA 908

dopamine D2 receptor antagonist; metabolite of remoxipride; structure given in first source; RN given refers to cpd without isomeric designation

Also Known As:

5-bromo-N ((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-6-methoxybenzamide; FLA 908, (+-)-isomer; FLA 908, (S)-isomer; FLA-908; NCQ 181; NCQ-181

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Hypothermia 12/01/1993 - "However, analysis of the effectiveness of the DA receptor blockade (blockade of d-amphetamine locomotion or DA agonist hypothermia) after intraperitoneal or subcutaneous administration suggested that FLA 797 (-)/FLA 908 (-) may only contribute marginally to the D2 receptor-blocking activity of remoxipride in the rat. "
2.	Catalepsy 12/01/1993 - "Among the metabolites tested, the phenolic compounds FLA 797 (-) and FLA 908 (-) were much more effective than remoxipride in inducing catalepsy, which is consistent with a higher affinity for [3H] raclopride labelled striatal D2 receptors. "

1.	Raclopride
2.	Remoxipride
3.	Dextroamphetamine (Dexedrine)
4.	FLA 797