GI 90291

major metabolite of remifentanil

Also Known As:

4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine propionic acid; GI-90291; GI90291; GR 90291; GR 90291C; GR-90291; GR90291; 1-Piperidinepropanoic acid, 4-(methoxycarbonyl)-4-((1-oxopropyl)phenylamino)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - GI 90291: 2

Related Diseases

1.	Renal Insufficiency (Renal Failure) 09/01/1997 - "The steady-state concentration of GR90291 is likely to be more than 25 times higher in persons with renal failure. " 09/01/1997 - "Patients with renal failure showed a marked reduction in the elimination of GR90291; the half-life of the metabolite increased from 1.5 h in the controls to more than 26 h in patients with renal failure. "
2.	Liver Diseases (Liver Disease) 04/01/1996 - "The pharmacokinetics of remifentanil and GR90291 are unchanged in persons with severe, chronic liver disease. "

Related Drugs and Biologics

1.	Remifentanil (Ultiva)