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poly(ethyleneglycol-lactide)

an artificial biodegradable polymer microsphere; used as a drug carrier

Also Known As:

PEGL

Networked: 6 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Li, Ankang: 1 article (12/2020)
2.	Li, Huifang: 1 article (12/2020)
3.	Li, Ke: 1 article (12/2020)
4.	Tang, Lixia: 1 article (12/2020)
5.	Wei, Bing: 1 article (12/2020)
6.	Xu, Yuancheng: 1 article (12/2020)
7.	Zhang, Yan: 1 article (12/2020)
8.	Coler-Reilly, Ariella: 1 article (03/2013)
9.	Kubota, Yoshiki: 1 article (03/2013)
10.	Nagasawa, Teruaki: 1 article (03/2013)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2012 - "In the in vivo studies utilizing solid tumor-bearing rat, it was confirmed that PEGL-RA delivered remarkably larger amount of RA to tumor tissue and provided more significant anti-tumor activity than free RA. " 07/01/2008 - "In a human ovarian carcinoma mouse model, combination treatment with H-PEGL (0.4 mg/day for 30 days; intraperitoneal) and DDP (5 mg/kg on days 7, 11, 15, 19; intraperitoneal) acted synergistically to inhibit tumor growth by 91.48% without notable toxicity, but H-PEGL and DDP alone only inhibit tumor growth by 66.83% and 52.5% as compared to the NaCl solution control, respectively. " 01/01/2002 - "Previously we reported that encapsulation of tumor necrosis factor-alpha (TNF) in pegylated (STEALTH) liposomes (TNF-PEGL) dramatically improved circulation times of the protein and augmented accumulation in tumor tissue. "
2.	Ovarian Neoplasms (Ovarian Cancer) 07/01/2008 - "Our results showed us a splendid prospect of the clinical application of combination treatment on patients suffering from ovarian cancer with H-PEGL and DDP." 03/01/2013 - "PEGL-DOX is an excellent treatment for recurrent ovarian cancer that rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in Hand-Foot Syndrome (HFS). "
3.	Cardiotoxicity 03/01/2013 - "PEGL-DOX is an excellent treatment for recurrent ovarian cancer that rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in Hand-Foot Syndrome (HFS). "
4.	Hand-Foot Syndrome 03/01/2013 - "PEGL-DOX is an excellent treatment for recurrent ovarian cancer that rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in Hand-Foot Syndrome (HFS). "
5.	Weight Loss (Weight Reduction) 01/01/2002 - "Even at a TNF dose of 200 microg/kg TNF, repeated administration of TNF-PEGL did not result in severe weight loss or cause diarrhea. "

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Proteins (Proteins, Gene)
4.	Streptozocin (Streptozotocin)
5.	Solutions
6.	Quercetin
7.	Cisplatin (Platino)
8.	liposomal honokiol
9.	liposomal doxorubicin (Doxil)