lumbrokinase

04/01/2013 - "Interestingly, lumbrokinase treatment markedly reduced the proteinuria and improved the glomerulosclerosis and tubulointerstitial fibrosis in diabetic rats. "
09/01/2015 - "Lumbrokinase from earthworm extract ameliorates second-hand smoke-induced cardiac fibrosis."
09/01/2015 - "Dilong, an edible earthworm extract used in Chinese medicine and its bioactive fibrinolytic enzyme product-lumbrokinase, when administered in rats, restricted the SHS exposure induced cardiac fibrosis and provided cardio-protection. "

04/11/2022 - "Lumbrokinase has been widely used for patients with acute ischemic stroke (AIS) in China; however, because rigorously designed studies are lacking, safety and efficacy of lumbrokinase in the treatment of acute ischemic stroke remains largely unknown. "
12/15/2022 - "We suggest that lumbrokinase is potential as an adjuvant treatment for ischemic stroke."
12/15/2022 - "Lumbrokinase regulates endoplasmic reticulum stress to improve neurological deficits in ischemic stroke."
11/01/2013 - "We aimed to assess the effects of one-year therapy with oral lumbrokinase enteric-coated capsules on secondary ischemic stroke prevention. "
12/15/2022 - "Our evidence indicates that post-stroke treatment with lumbrokinase protects against ischemic stroke, thereby regulating ER stress through the collective inhibitory effect of the IRE1 signaling pathways to decrease apoptosis, autophagy, and inflammatory responses. "

01/01/2019 - "Lumbrokinase effects on pro- and anti-apoptotic gene expression in Wistar rats with testicular torsion."
01/01/2019 - "This study was performed to determine the therapeutic efficacy of lumbrokinase for treating ischemia-reperfusion (IR) injury-induced bilateral testicular torsion. "

01/01/2019 - "This study was performed to determine the therapeutic efficacy of lumbrokinase for treating ischemia-reperfusion (IR) injury-induced bilateral testicular torsion. "

12/15/2022 - "Lumbrokinase significantly attenuated infarct volume and improved neurological dysfunction. "
10/01/2016 - "The animals were treated with/without lumbrokinase and the severities of I-R-induced arrhythmias and infarction were compared. "
03/01/2006 - "Lumbrokinase decreased the infarct size of myocardium in a dose-dependent manner. "