2- (4- chlorophenyl)- 4,5- diphenyl- 2- imidazoline hydrochloride

07/01/1995 - "The arthritis score was markedly suppressed in the groups treated with dexamethasone and TA-383. "
07/01/1995 - "Effect of a novel anti-rheumatic drug, TA-383, on type II collagen-induced arthritis."
06/01/1997 - "In vivo, TA-383 (0.4 mg/kg, p.o.) has suppressive effects on picryl chloride-induced delayed type hypersensitivity and type II collagen-induced arthritis in mice. "
07/01/1995 - "These findings suggest that the histopathological examination of the joints of the animal model is useful for the evaluation of anti-rheumatic drugs, and that TA-383 has suppressive effects on type II collagen-induced arthritis, an animal model for human rheumatoid arthritis."
05/01/1993 - "Effect of a novel anti-rheumatic drug, TA-383, on type II collagen-induced arthritis--suppressive effect of TA-383 on interleukin 6 production."

06/01/1997 - "In vivo, TA-383 (0.4 mg/kg, p.o.) has suppressive effects on picryl chloride-induced delayed type hypersensitivity and type II collagen-induced arthritis in mice. "

07/01/1995 - "These findings suggest that the histopathological examination of the joints of the animal model is useful for the evaluation of anti-rheumatic drugs, and that TA-383 has suppressive effects on type II collagen-induced arthritis, an animal model for human rheumatoid arthritis."