growth arrest-specific protein 6

Gas6 is a member of the vitamin K-dependent proteins related to protein S; a variety of receptors bind Gas6 as a ligand

Also Known As:

AXL stimulatory factor, human; AXSF protein, human; GAS6 protein, human; Gas6 protein, mouse; Gas6 protein, rat; growth arrest specific 6 protein, mouse; growth arrest specific 6, rat; growth arrest-specific 6 protein, human; growth arrest-specific protein 6, human; growth-potentiating factor, 70-kDa; growth-potentiating factor, 70-kDa, human

Networked: 52 relevant articles (3 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Dahlbäck, Björn: 4 articles (06/2011 - 01/2010)
2.	Bassyouni, Rasha H: 3 articles (01/2020 - 12/2012)
3.	Ekman, Carl: 3 articles (06/2011 - 01/2010)
4.	Bassyouni, Iman H: 2 articles (01/2017 - 12/2012)
5.	Coppa, Gene F: 2 articles (12/2015 - 12/2013)
6.	Giangola, Matthew D: 2 articles (12/2015 - 12/2013)
7.	Nicastro, Jeffrey: 2 articles (12/2015 - 12/2013)
8.	Rajayer, Salil R: 2 articles (12/2015 - 12/2013)
9.	Wang, Ping: 2 articles (12/2015 - 12/2013)
10.	Yang, Weng-Lang: 2 articles (12/2015 - 12/2013)

Related Diseases

1.	Brain Injuries (Brain Injury) 08/01/2022 - "Growth-arrest-specific protein 6 (Gas6) exerts nervous protective effects on acute brain injury. " 01/01/2022 - "Growth arrest-specific protein 6 (Gas6) may harbor protective effects in acute brain injury. "
2.	Sepsis (Septicemia) 01/01/2006 - "Elevated growth-arrest-specific protein 6 plasma levels in patients with severe sepsis." 04/01/2016 - "Protective Effects of Growth Arrest-Specific Protein 6 (Gas6) on Sepsis-Induced Acute Kidney Injury." 12/01/2013 - "Growth arrest-specific protein 6 attenuates neutrophil migration and acute lung injury in sepsis." 01/01/2010 - "Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes." 01/18/2022 - "Soluble tyrosine kinase receptor Mer (sMer) and its ligand Growth arrest-specific protein 6 (Gas6) are predictors of mortality in patients with sepsis. "
3.	Acute Kidney Injury (Acute Renal Failure) 04/01/2016 - "Protective Effects of Growth Arrest-Specific Protein 6 (Gas6) on Sepsis-Induced Acute Kidney Injury."
4.	Neoplasms (Cancer) 01/01/2022 - "Overexpression of tumor-associated growth arrest-specific protein 6 (Gas6) is found in many tumor entities. " 11/01/2021 - "Several studies have demonstrated that growth arrest-specific protein 6 (Gas6) and Axl are highly expressed in various tumor tissues, such as renal cell and esophageal carcinoma. " 12/01/2020 - "Axl receptor tyrosine kinase (RTK) and its ligand, growth arrest-specific protein 6 (Gas6), are involved in several biological functions and participate in the development and progression of a range of malignancies and autoimmune disorders. " 01/01/2020 - "Growth arrest-specific protein 6 (GAS6)-induced MER phosphorylation is often unstable and difficult to detect without pervanadate pretreatment in human cancer cells, posing a challenge for the development of selective MER kinase inhibitors. " 01/01/2019 - "Growth arrest-specific protein 6 (Gas6), one of the endogenous ligands of TAM receptors (Tyro3, Axl, and Mertk), is confirmed to have beneficial functions in hemostasis, inflammation, and cancer growth. "
5.	Atherosclerosis 02/01/2019 - "Pre-clinical studies suggest that growth arrest-specific protein 6 (Gas6), a member of the vitamin K dependent family of proteins, is implicated in atherosclerosis. "

Related Drugs and Biologics

1.	Vitamin K
2.	Proteins (Proteins, Gene)
3.	Protein S
4.	Lipids
5.	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)
6.	Ligands
7.	Biomarkers (Surrogate Marker)
8.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
9.	Proto-Oncogene Proteins c-akt (Protein Kinase B)
10.	Mitogen-Activated Protein Kinases