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Innovin

recombinant thromboplastin supplied by Baxter Diagnostics

Also Known As:

rthromboplastin

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Thromboplastin: 4648
        Innovin: 5
  - Recombinant Proteins: 2754
    - Innovin: 5
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Thromboplastin: 4648
    - Innovin: 5

Experts

1.	Andersen, Søren: 1 article (08/2010)
2.	Lethagen, Stefan: 1 article (08/2010)
3.	Sørensen, Brit B: 1 article (08/2010)
4.	Viuff, Dorthe: 1 article (08/2010)
5.	Kitchen, Steve: 1 article (04/2010)
6.	Maclean, Rhona: 1 article (04/2010)
7.	Sermon, Anne M: 1 article (04/2010)
8.	Smith, Julie M: 1 article (04/2010)
9.	Clausen, Niels: 1 article (01/2009)
10.	Ezban, Mirella: 1 article (01/2009)

Related Diseases

1.	Thrombocytopenia (Thrombopenia) 01/01/2009 - "The present study evaluated dynamic coagulation profiles, platelet aggregation, and thrombin generation in whole blood (WB) from eight children with thrombocytopenia during chemotherapy, and the haemostatic potential of platelets (+60 x 10(9)/l), recombinant factor VIIa (rFVIIa - NovoSeven), and a potent rFVIIa analogue (NN1731) both at 1 and 4 microg/ml. Dynamic WB coagulation profiles were recorded by thrombelastometry employing activation with tissue factor (TF - Innovin) at low concentrations. "
2.	Sinusitis 06/01/2008 - "This study investigates the effect on adhesion formation and wound healing in a sheep model of chronic sinusitis of three topical agents: recombinant tissue factor (rTF, Dade Innovin, Marburg, Germany), poly-ethylene glycol (SprayGel, Confluent Surgical, Waltham, MA), and a novel chitosan-dextran derivative gel (CD, Department of Chemistry, University of Otago, Dunedin, New Zealand). "
3.	Pancreatic Neoplasms (Pancreatic Cancer) 03/01/2023 - "We determined the ability of 4 commercial ELISAs (Imubind, Quantikine, Human SimpleStep, and CD142 Human) to detect recombinant human TF (Innovin) (12.5-100 pg/mL), TF-positive EVs isolated from the culture supernatant from a human pancreatic cancer cell line (57 pg/mL), TF in plasma containing low levels of EV TF activity (1.2-2.6 pg/mL) from lipopolysaccharide-stimulated whole blood, and plasma containing high levels of EV TF activity (151-696 pg/mL) from patients with acute leukemia. "
4.	Liver Diseases (Liver Disease) 04/01/2010 - "Prothrombin times from 60 patients with liver disease were determined using three working thromboplastin reagents; Innovin, Thromborel S and Thromboplastin C and two reference thromboplastins; rTF/95 and RBT/05. "
5.	Leukemia 03/01/2023 - "We determined the ability of 4 commercial ELISAs (Imubind, Quantikine, Human SimpleStep, and CD142 Human) to detect recombinant human TF (Innovin) (12.5-100 pg/mL), TF-positive EVs isolated from the culture supernatant from a human pancreatic cancer cell line (57 pg/mL), TF in plasma containing low levels of EV TF activity (1.2-2.6 pg/mL) from lipopolysaccharide-stimulated whole blood, and plasma containing high levels of EV TF activity (151-696 pg/mL) from patients with acute leukemia. "

Related Drugs and Biologics

1.	Thromboplastin (Tissue Factor)
2.	Chitosan
3.	Ethylene Glycol (Monoethylene Glycol)
4.	Thrombin
5.	Dextrans (Dextran)
6.	NN1731
7.	recombinant FVIIa (rFVIIa)
8.	Tissue Plasminogen Activator (Alteplase)
9.	Lipopolysaccharides
10.	Kaolin

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)