tebufenozide (Mimic)

07/01/1997 - "However, it is most helpful in confirming atypical variants of HCC, which may mimic other tumors."
01/01/2015 - "The systemic injection of miR-34a mimic-loaded nanoparticles significantly inhibited tumor growth and translated into improved survival of the laboratory mice. "
05/01/2011 - "Ovarian stroma in HL may mimic solid tumorous components in mucinous tumors; however, high ADC reflecting edematous, luteinized stroma may be helpful for the diagnosis of HL."
08/01/2008 - "These findings suggest that this model may mimic the behavior of IMSCTs following operative resection in humans and thus may be used to examine efficacy of new treatment options for high-grade intramedullary tumors."
10/01/2014 - "Calorimetric and permeability studies showed that N-acylation and even more the repeat derivative of LF11-322 leads to strongly improved interaction with the cancer mimic PS, whereas only the N-acyl derivative also slightly affects PC. "

03/01/2009 - "An effective vaccine should mimic protection provided by natural infection and provide protection against the most common rotavirus serotypes (ie, G1, G2, G3, G4, G9) and be able to decrease disease severity, reduce hospitalizations, and decrease disease-related costs."
10/01/2005 - "The development of live attenuated vectors shows promise in the field of Leishmania vaccination because these organisms mimic more effectively the course of real infections and can elicit potent activation of the immune system. "
02/01/2010 - "However, infection was well tolerated and resulted in a non-significant improvement in airway responsiveness, indicating that further studies that mimic more closely natural infection are feasible and should be undertaken."
05/15/1997 - "It has to mimic what already occurs in a minority of unvaccinated individuals--namely, rapid clearance of infection or reduction of viral load to a level that does not produce symptoms or permit transmission to others. "
11/01/2009 - "Although the new paradigm that emerges raises concerns about the adequacy of existing animal models, it also suggests ways to modify these models to better mimic the complexities of human infection and therefore serve as appropriate models in which to test the safety and efficacy of vaccine candidates against C. "

01/01/2012 - "In this study an in vitro Pseudomonas aeruginosa biofilm model was developed to mimic potential surface wound biofilms. "
07/03/2010 - "The objective of this study was to develop an acellular provisional matrix to mimic the extracellular matrix (ECM) of a wound site, and to evaluate its potential for in vivo dermal regeneration. "
01/01/2007 - "By adapting skin equivalent models of human skin to study wound reepithelialization, it has been shown that several key responses, including cell proliferation, migration, differentiation, growth-factor responsiveness and protease expression, will mimic the response seen in human skin. "
10/01/2006 - "The aim of the present study was to test memory for information under conditions of extreme arousal in an analogue design to mimic hyperarousal during trauma exposure. "
01/01/2004 - "Current studies using this model employ a full-thickness wound placed atop a nonwounded dermis to mimic a partial-thickness wound. "

07/22/2013 - "In this sense, PHD inhibition has been proposed to mimic, at least in part, the protective effects of exposure to hypoxia. "
12/01/2015 - "In this study, we demonstrated that both hypoxia and hypoxia-mimic conditions decreased NcoA2 protein expression in HEK293T cells. "
05/01/2015 - "In this study, we investigated the effects of knockdown of HIF subunit genes to elucidate how HIF subunit genes may be involved in the radioresistance acquired by HeLa cells following exposure to a hypoxia mimic. "
01/07/2015 - "The mimic reductive activation study revealed that compound 15c exerted reductive activation properties under hypoxia, which were consistent with the in vitro metabolic study, wherein 15c was easily reductive activated under hypoxia and much more stable under normoxia. "
11/01/2014 - "In this study, adult Sprague-Dawley rats were exposed to intermittent chronic hypoxia for 4 wk to mimic a severe HPH condition. "

09/10/2003 - "The dex70 was also effective in normoxic slices (400 microm) after hypoosmotic stress altered the ECS to mimic ischemia. "
01/01/2015 - "In mouse model of critical limb ischemia, miR-27b mimic also improved tissue re-vascularization and perfusion. "
01/01/2012 - "To study this disease, ischemia/reperfusion (I/R) models are widely used to mimic the process of transient blockage and subsequent recovery of cardiac coronary blood supply. "
05/01/1996 - "The present study is designed to test whether PKC activation could mimic and PKC inhibition could block the PC effects on intracellular acidification during ischemia and on stunning during reflow in Langendorff perfused rat hearts. "
11/01/1991 - "This cell culture system may be used to form the basis for future studies of the electrophysiology and transport properties of retinal ganglion cells under normal culture conditions and under adverse conditions such as those that mimic ischemia or mechanical deformation."