pentetreotide (OctreoScan)

an indium-labelled somatostatin analog for imaging of somatostatin receptor positive tumours; OctreoScan is tradename for indium In 111 pentetreotide

Also Known As:

OctreoScan; indium In 111 pentetreotide; 111 In -pentetreotide; 111-indium-pentetreotide; In-111 pentetreotide; OctreoScan 111; indium ln-111 pentetreotide; indium-pentetreotide; L-Cysteinamide, N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (3-8)-disulfide, (R-,(R*,R*))-

Networked: 361 relevant articles (24 outcomes, 28 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Rubello, D: 4 articles (03/2016 - 12/2003)
2.	Nikou, George C: 4 articles (01/2011 - 05/2005)
3.	Toubanakis, Christos: 4 articles (01/2011 - 05/2005)
4.	Krenning, Eric P: 4 articles (05/2010 - 04/2003)
5.	Chen, Clara C: 3 articles (10/2016 - 09/2002)
6.	Stokkel, Marcel P M: 3 articles (05/2016 - 05/2003)
7.	Sarmiento, Juan M: 3 articles (07/2015 - 01/2003)
8.	Menda, Yusuf: 3 articles (08/2014 - 02/2004)
9.	Delpassand, Ebrahim S: 3 articles (01/2014 - 06/2008)
10.	Carrasquillo, Jorge A: 3 articles (08/2012 - 09/2002)

Related Diseases

1.	Neoplasms (Cancer) 12/15/1997 - "This study explores the efficacy of OctreoScan and a newly developed handheld gamma detector probe (H-probe2) for the localization of neuroendocrine abdominal tumors. " 10/01/1996 - "The aim of this study was to evaluate the ability of Octreoscan scintigraphy to detect such tumors. " 01/01/1994 - "The results are the following: 2 patients of group A (secreting tumors) had a positive three-step ISG, whereas all the patients but one of the same group had a positive pentetreotide study; all the patients of group B (nonsecreting tumors) had a positive three-step ISG and 4 had a positive pentetreotide scintigraphy. " 10/01/2021 - "Enhanced computed tomography and OctreoScan scintigraphy revealed a pancreatic tumor (diameter, 13 mm) with radiotracer accumulation. " 10/01/2019 - "Tumor site and size at diagnosis were determined by ultrasound, CT-scan, angiography, PETscan, octreoscan and intraoperative ultrasound. "
2.	Carcinoid Tumor (Carcinoid) 01/01/1999 - "We conclude that: 1. the octreoscan scintigraphy in the follow-up of resected carcinoids can give false-positive results and 2. in consequence, the mediastinoscopy is a discriminating investigation in case of mediastinal lymph nodes disease." 10/01/2022 - "An abdominal Magnetic Resonance Imaging scan revealed multiple focal loci in the liver whose histological examination revealed a carcinoid tumor confirmed by an Octreoscan. " 12/01/2020 - "A 55-year-old woman with an antecedent history of resected carcinoid tumour of the ileocecal junction underwent whole-body In-111 Octreoscan single-photon emission computed tomography in the context of her follow-up. " 04/01/2017 - "A In-pentetreotide scan showed intense uptake; furthermore, fine needle aspiration biopsy yielded neuroendocrine cells confirming the carcinoid hypothesis. " 12/01/2016 - "A subsequent octreoscan revealed no primary sites of carcinoid tumor. "
3.	Neoplasm Metastasis (Metastasis) 07/01/2005 - "OCTREOSCAN revealed a solitary lesion in the right hepatic lobe, not detected by all the previous studies, while it detected, as a whole, the primary lesion in 10/11 (91%), and the metastases in 3/4 (75%) pts. In 7/11 (63.6%) the primary lesion was located in the pancreas, whereas in the rest it was in the duodenum or retroperitoneum. " 03/01/2019 - "Workup octreoscan showed newly developed diffuse bone metastases, in addition to the persistent liver metastases. " 05/01/2010 - "Octreoscan and whole body CT scan confirmed a locally advanced disease, in the absence of metastases. " 01/01/2008 - "OctreoScan showed avid uptake in 77.8% of patients with hepatic metastases. " 08/01/2007 - "Chest CT-scan identified local extension and lung-associated lesions; octreoscan was performed to detect distant metastases. "
4.	Neuroendocrine Tumors (Neuroendocrine Tumor) 07/01/2008 - "In-111 Octreoscan is considered the gold standard for imaging of neuroendocrine tumors (NET). " 07/01/2007 - "In-111 Octreoscan is considered the gold standard for imaging of neuroendocrine tumors (NET). " 12/01/2001 - "The study describes the results of Octreoscan SPET (OCTSPET) qualitative and semi-quantitative evaluation in 38 patients with suspected pancreatic neuroendocrine tumors. " 12/01/2022 - "Octreoscan confirmed the primary hepatic origin of neuroendocrine tumor. " 10/01/2018 - "Diffuse involvement of the pancreas in neuroendocrine tumor is a rare presentation, and its appearance on In-111 pentetreotide scan has not been reported earlier in the literature. "
5.	Thyroid Neoplasms (Thyroid Cancer) 05/01/1997 - "Furthermore, in 4 of these patients as well as in all medullary thyroid carcinoma patients 111 MBq (3 mCi) of 99mTc-(V)DMSA were applied i.v. I week prior to the pentetreotide/mlBG scans. " 05/01/1994 - "In-111 pentetreotide scintigraphy of 10 patients with residual or metastatic medullary thyroid carcinoma is described. " 01/01/2017 - "Scintigraphy with 111In-pentetreotide (Octreoscan) indicated a suspected thyroid nodule, later confirmed to represent medullary thyroid carcinoma lesion. " 01/01/1993 - "In a prospective study, 18 patients with recurrent medullary thyroid carcinoma (MTC) underwent magnetic resonance imaging (MRI) of the neck and mediastinum and somatostatin receptor scintigraphy (SRS) with 111In-labeled pentetreotide. " 06/01/1996 - "Indium-111 pentetreotide scintigraphy was performed in two patients for the localization of recurrent medullary thyroid carcinoma treated by surgery and external radiotherapy 1 and 10 years earlier. "

Related Drugs and Biologics

1.	Somatostatin Receptors (Somatostatin Receptor)
2.	Octreotide (Sandostatin)
3.	Somatostatin (Somatotropin Release-Inhibiting Factor)
4.	pentetreotide (OctreoScan)
5.	Indium-111
6.	3-Iodobenzylguanidine (Iobenguane)
7.	Adrenocorticotropic Hormone (ACTH)
8.	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
9.	Indium
10.	Radioisotopes (Radionuclides)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Radiotherapy
4.	Thyroidectomy
5.	Intravenous Injections

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