2,4,4'-trichlorobiphenyl

Also Known As:

2,4,4'-TCB; PCB 28; PCB-28

Networked: 11 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        Polychlorinated Biphenyls: 1778
        2,4,4'-trichlorobiphenyl: 11
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Polychlorinated Biphenyls: 1778
        2,4,4'-trichlorobiphenyl: 11
- Dioxins and Dioxin-like Compounds: 5
  - Polychlorinated Biphenyls: 1778
    - 2,4,4'-trichlorobiphenyl: 11

Experts

1.	Aune, Marie: 2 articles (09/2016 - 06/2011)
2.	Glynn, Anders: 2 articles (09/2016 - 06/2011)
3.	Lignell, Sanna: 2 articles (09/2016 - 06/2011)
4.	Cortese, Bernardo: 2 articles (05/2011 - 08/2010)
5.	Bertram, Jens: 1 article (06/2020)
6.	Felten, Michael K: 1 article (06/2020)
7.	Fobil, Julius N: 1 article (06/2020)
8.	Kaifie, Andrea: 1 article (06/2020)
9.	Kraus, Thomas: 1 article (06/2020)
10.	Küpper, Thomas: 1 article (06/2020)

Related Diseases

1.	Weight Loss (Weight Reduction) 09/01/2016 - "We analysed POPs (PCB 28, PCB 153, HCB, DDE) in HM at 12 and 24 weeks postpartum from 32 women who participated in a randomized, 2 × 2 factorial trial of diet and exercise for postpartum weight loss. " 06/01/2011 - "In a multiple regression model, levels of PCBs (except PCB 28), PCDD/Fs and BDE-153 were positively associated with age of the mother and weight loss after delivery and inversely associated with pre-pregnancy BMI (body mass index) and weight gain during pregnancy. " 05/01/2002 - "Changes in organochlorine concentrations were negatively associated with changes in serum T(3) concentration (significantly for p,p'-DDT, HCB, Aroclor 1260, PCB 28, PCB 99, PCB 118, and PCB 170) and with changes in RMR adjusted for weight loss (significantly for HCB and PCB 156). "
2.	Body Weight (Weight, Body) 07/01/2006 - "After 8 or 16 weeks of PCB treatment (50 and 150 micromol/kg body weight per week), each congener was recovered in the liver according to the dose levels applied, with PCB 28, at the same dose level, showing nine- to 16-fold higher hepatic levels than PCB 101 (approximately, 44 micromol/kg versus 5 micromol/kg liver at low dose, 145 micromol/kg versus 9 micromol/kg liver at high dose). " 05/15/1996 - "The objective of the present study was to investigate whether neonatal exposure to single PCB (polychlorinated biphenyl) congeners 2,4,4'-trichlorobiphenyl (IUPAC 28), 2,2',5,5'-tetrachlorobiphenyl (IUPAC 52), 2,3',4,4',5-pentachlorobiphenyl (IUPAC 118) and 2,3,3',4,4',5-hexachlorobiphenyl (IUPAC 156) when given as one single dose (0.7-14 μmol/kg body weight per os) to 10-day-old male NMRI mice could induce persistent neurotoxic effects in the adult animal. "
3.	Unstable Angina 05/01/2011 - "In the PICCOLETO randomised trial, patients with stable or unstable angina undergoing PCI of small coronary vessels (≤ 2.75 mm) were randomised to the Dior PCB (28 patients) or the Taxus DES (29 patients). " 08/01/2010 - "In the PICCOLETO randomised clinical trial, patients with stable or unstable angina undergoing PCI of small coronary vessels (< or = 2.75 mm) were randomised to Dior PCB (28 patients) or Taxus DES (29 patients). "
4.	Weight Gain 06/01/2011 - "In a multiple regression model, levels of PCBs (except PCB 28), PCDD/Fs and BDE-153 were positively associated with age of the mother and weight loss after delivery and inversely associated with pre-pregnancy BMI (body mass index) and weight gain during pregnancy. "
5.	Endometriosis 02/01/2023 - "The consistent results were found in case of lead, PCB-28, PCB-138, PCB-153, PCB-180, PCB-201, 1,2,3,7,8 - PeCDD, 2,3,4,7,8 - PeCDF and all described OCPs, showing the increased risk of endometriosis. "

Related Drugs and Biologics

1.	2,3',4,4',5-pentachlorobiphenyl
2.	2,4,5,2',4',5'-hexachlorobiphenyl
3.	Polychlorinated Biphenyls (PCBs)
4.	Hexachlorobenzene (HCB)
5.	Dichlorodiphenyl Dichloroethylene (DDE)
6.	2,3,3',4,4',5-hexachlorobiphenyl
7.	2,5,2',5'-tetrachlorobiphenyl
8.	DDT
9.	Polychlorinated Dibenzodioxins (TCDD)
10.	2,2',3,3',4,4',5-heptachlorobiphenyl