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thrombin aptamer

nucleotide sequence given in first source; a synthetic polynucleotide

Also Known As:

GGTTGGTGTGGTTGG; GS 522; GS-522; d(GGTTGGTGTGGTTGG); thrombin-binding aptamer

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Nucleotide Aptamers: 598
        thrombin aptamer: 5

Experts

1.	Dong, Cheng: 1 article (12/2015)
2.	Gaddes, Erin R: 1 article (12/2015)
3.	Gydush, Gregory: 1 article (12/2015)
4.	Lee, Deborah: 1 article (12/2015)
5.	Wang, Yong: 1 article (12/2015)
6.	Hu, Bingqiang: 1 article (07/2015)
7.	Hu, Jun: 1 article (07/2015)
8.	Liu, Qiaoling: 1 article (07/2015)
9.	Tan, Weihong: 1 article (07/2015)
10.	Wang, Jing: 1 article (07/2015)

Related Diseases

1.	Neoplasms (Cancer) 12/10/2015 - "Regulation of fibrin-mediated tumor cell adhesion to the endothelium using anti-thrombin aptamer." 11/18/2011 - "Selective recognition of co-assembled thrombin aptamer and docetaxel on mesoporous silica nanoparticles against tumor cell proliferation." 07/01/2015 - "Their binding, internalization, and antiproliferation activity in cancer and noncancer cells were investigated by flow cytometry and 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay, and compared with those of nucleolin-binding AS1411 and thrombin-binding aptamer. "
2.	Thrombosis (Thrombus) 10/01/2008 - "4-thio-deoxyuridylate-modified thrombin aptamer and its inhibitory effect on fibrin clot formation, platelet aggregation and thrombus growth on subendothelial matrix."
3.	Cholera 04/15/2013 - "An immunosensor configuration based on the immobilization of biotin-tagged cholera toxin was applied to the detection of anti-cholera antibody while the aptasensor based on the immobilization of histidine-tagged thrombin aptamer was tested for thrombin determination. "

Related Drugs and Biologics

1.	Fibrin
2.	Thrombin
3.	Silicon Dioxide (Silica)
4.	Histidine (L-Histidine)
5.	Cholera Toxin
6.	Biotin (Vitamin H)
7.	Nucleolin
8.	Docetaxel (Taxotere)
9.	AGRO 100
10.	3- (4,5- dimethylthiazol- 2- yl)- 5- (3- carboxymethoxyphenyl)- 2- (4- sulfophenyl)- 2H- tetrazolium