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tyrosyl- isoleucyl- glycyl- seryl- argininamide

a synthetic peptide; exhibits antiadhesive cellular activity

Also Known As:

Tyr-Ile-Gly-Ser-Arg-NH2; YIGSR-NH2

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - tyrosyl-isoleucyl-glycyl-seryl-argininamide: 1

Experts

1.	Izdebski, Jan: 1 article (05/2004)
2.	Opolski, Adam: 1 article (05/2004)
3.	Oriowska, Alicja: 1 article (05/2004)
4.	Salwa, Jan: 1 article (05/2004)
5.	Wietrzyk, Joanna: 1 article (05/2004)
6.	Witkowska, Ewa: 1 article (05/2004)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2004 - "Eleven analogues of the laminin pentapeptide amide fragment Tyr-Ile-Gly-Ser-Arg-NH2 (YIGSR-NH2) corresponding to a B1 chain fragment of the glycoprotein laminin have been synthesized by the solid phase method, and their biological activity has been studied in vitro by a cell adhesion assay: all of them inhibited the adhesion of LLC tumor cells to laminin. "
2.	Neoplasm Metastasis (Metastasis) 05/01/2004 - "Analogue DatIGSHar-NH2 was selected for an experimental pulmonary metastasis assay in vivo: it had higher antimetastatic activity than YIGSR-NH2."

Related Drugs and Biologics

1.	Laminin (Merosin)
2.	Glycoproteins (Glycoprotein)
3.	Amides