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L 692429
stimulates release of growth hormone; RN refers to (R)-isomer; structure given in first source
Also Known As:
L 692,429; L-692,429; L-692429; Butanamide, 3-amino-3-methyl-N-(2,3,4,5-tetrahydro-2-oxo-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-1-benzazepin-3-yl)-, (R)-
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Tetrazoles: 14
L 692429: 3
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzazepines: 5
L 692429: 3
Related Diseases
1.
Pituitary Neoplasms (Pituitary Adenoma)
03/17/1995 - "
We examined the effects of L-692,429 on cultured human pituitary tumors removed from patients with acromegaly.
"
03/17/1995 - "
The growth hormone secretagogue, L-692,429, induces phosphatidylinositol hydrolysis and hormone secretion by human pituitary tumors.
"
2.
Obesity
04/01/1997 - "
Effect of obesity and feeding on the growth hormone (GH) response to the GH secretagogue L-692,429 in young men.
"
3.
Flushing
11/01/1993 - "
Facial flushing or a warm sensation were reported in 4 subjects, primarily at dose levels of 0.2 mg/kg L-692,429 or more, but no other clinical or laboratory adverse experiences appeared related to drug treatment.
"
4.
Acromegaly
03/17/1995 - "
We examined the effects of L-692,429 on cultured human pituitary tumors removed from patients with acromegaly.
"
Related Drugs and Biologics
1.
Growth Hormone (Somatotropin)
2.
Secretagogues
3.
Phosphatidylinositols (Phosphatidylinositol)
4.
Hormones (Hormone)