archaeosine

post-transcriptional modification seen in archaeal RNA; structure given in first source

Also Known As:

2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide; 1H-Pyrrolo(2,3-d)pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Guanosine: 1156
        archaeosine: 3
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Guanosine: 1156
      - archaeosine: 3
  - Ribonucleosides: 49
    - Guanosine: 1156
      - archaeosine: 3

Experts

1.	Iwata-Reuyl, Dirk: 2 articles (01/2017 - 02/2012)
2.	de Crécy-Lagard, Valérie: 2 articles (01/2017 - 02/2012)
3.	Ando, Kaori: 1 article (12/2019)
4.	Hirata, Akira: 1 article (12/2019)
5.	Hiura, Keita: 1 article (12/2019)
6.	Hori, Hiroyuki: 1 article (12/2019)
7.	Kawamura, Takuya: 1 article (12/2019)
8.	Nakada, Saori: 1 article (12/2019)
9.	Nomura, Yuichiro: 1 article (12/2019)
10.	Ogino, Hiromi: 1 article (12/2019)

Related Diseases

Arthrogryposis renal dysfunction cholestasis syndrome

12/01/2019 - "We propose that ArcS and RaSEA should be considered an archaeosine synthase α-subunit (lysine transferase) and β-subunit (q0kN-tRNA lyase), respectively."
01/01/2017 - "In the Euryarchaeota, the last step of the archaeosine biosynthetic pathway involves the amidation of a nitrile group on an archaeosine precursor to give formamidine, a reaction catalyzed by the enzyme Archaeosine Synthase (ArcS). "
02/17/2012 - "In Euryarchaeota, the G(+) precursor, 7-cyano-7-deazaguanine (preQ(0)), is inserted into tRNA by tRNA-guanine transglycosylase (arcTGT) before conversion into G(+) by ARChaeosine Synthase (ArcS). "

Related Drugs and Biologics

1.	Transferases
2.	Transfer RNA (tRNA)
3.	Nitriles
4.	Lysine (L-Lysine)
5.	Enzymes
6.	formamidine (formamidinium)
7.	queuine tRNA-ribosyltransferase
8.	7-cyano-7-deazaguanine