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N-acetylglucosaminylphosphatidylinositol

Also Known As:

GlcNAc-PI; N-acetylglucosamine-phosphatidylinositol

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Amino Sugars: 110
  - Hexosamines: 733
    - Glucosamine: 1771
      - Acetylglucosamine: 922
        N-acetylglucosaminylphosphatidylinositol: 4
Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Glycerophospholipids: 689
        Phosphatidylinositols: 5099
        N-acetylglucosaminylphosphatidylinositol: 4

Related Diseases

1.	Lymphoma (Lymphomas) 08/01/1994 - "The biochemical basis of this deficiency is the lack of the first GPI biosynthesis intermediate GlcNAc-PI in the deficient cells corresponding to that in Thy-1- mouse lymphoma mutants of the class A. " 06/05/1991 - "Analysis of available lymphoma mutants deficient in Thy-1 surface expression revealed that extracts of the class A, C, and H mutants are completely defective in synthesizing GlcNAc-PI and GlcN-PI." 12/16/1994 - "The synthesis of the GlcN-PI(acyl) from either UDP-[6-3H]GlcNAc or [6-3H] GlcNAc-PI by murine lymphoma cell microsomes was greatly enhanced by the addition of either CoA or palmitoyl-CoA. "
2.	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 04/01/1994 - "Mutation in the X-linked class A gene was shown to be the cause of paroxysmal nocturnal hemoglobinuria, an acquired disease affecting hematopoietic stem cells in which the abnormal cells are deficient in GlcNAc-PI formation. "

Related Drugs and Biologics

1.	Uridine Diphosphate (UDP)
2.	Palmitoyl Coenzyme A (Palmitoyl CoA)
3.	Coenzyme A (CoA)