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N-acetylglucosaminylphosphatidylinositol
Also Known As:
GlcNAc-PI; N-acetylglucosamine-phosphatidylinositol
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Amino Sugars: 110
Hexosamines: 733
Glucosamine: 1771
Acetylglucosamine: 922
N-acetylglucosaminylphosphatidylinositol: 4
Lipids: 114793
Membrane Lipids: 1591
Phospholipids: 11903
Glycerophosphates: 118
Phosphatidic Acids: 358
Glycerophospholipids: 689
Phosphatidylinositols: 5099
N-acetylglucosaminylphosphatidylinositol: 4
Related Diseases
1.
Lymphoma (Lymphomas)
08/01/1994 - "
The biochemical basis of this deficiency is the lack of the first GPI biosynthesis intermediate GlcNAc-PI in the deficient cells corresponding to that in Thy-1- mouse lymphoma mutants of the class A.
"
06/05/1991 - "
Analysis of available lymphoma mutants deficient in Thy-1 surface expression revealed that extracts of the class A, C, and H mutants are completely defective in synthesizing GlcNAc-PI and GlcN-PI.
"
12/16/1994 - "
The synthesis of the GlcN-PI(acyl) from either UDP-[6-3H]GlcNAc or [6-3H] GlcNAc-PI by murine lymphoma cell microsomes was greatly enhanced by the addition of either CoA or palmitoyl-CoA.
"
2.
Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
04/01/1994 - "
Mutation in the X-linked class A gene was shown to be the cause of paroxysmal nocturnal hemoglobinuria, an acquired disease affecting hematopoietic stem cells in which the abnormal cells are deficient in GlcNAc-PI formation.
"
Related Drugs and Biologics
1.
Uridine Diphosphate (UDP)
2.
Palmitoyl Coenzyme A (Palmitoyl CoA)
3.
Coenzyme A (CoA)