echicetin

from Echis carinatus venom; inhibits binding of von Willebrand factor & alboaggregins to platelet glycoprotein Ib; MW 26 kDa, a dimer of 14 & 16 kDa subunits

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	De Meyer, Simon F: 1 article (04/2005)
2.	Deckmyn, Hans: 1 article (04/2005)
3.	Niu, Liwen: 1 article (04/2005)
4.	Teng, Maikun: 1 article (04/2005)
5.	Ulrichts, Hans: 1 article (04/2005)
6.	Vauterin, Stephan: 1 article (04/2005)
7.	Xu, Gufeng: 1 article (04/2005)
8.	Clemetson, J M: 1 article (04/2001)
9.	Clemetson, K J: 1 article (04/2001)
10.	Dörmann, D: 1 article (04/2001)

Related Diseases

1.

Thrombocytopenia (Thrombopenia) 04/15/2001 - "In vivo, echicetin probably activates platelets rather than inhibits platelet activation, as previously proposed, accounting for the observed induction of thrombocytopenia." 04/01/2005 - "Another thing of interest is that, although agkicetin-C did not agglutinate platelets in all conditions tested in vitro, it caused a severe thrombocytopenia in rats, suggesting a different mechanism than with flavocetin-A or echicetin."

Related Drugs and Biologics

1.	flavocetin A
2.	agkicetin