sairei-to

kampo & Chinese mixture of Bupleurum root, Alisma rhizome, Pinellia tuber, Scutellaria root, Atractylodes rhizome, Jujube fruit, Polyporus fungus, Ginseng, Hoelen, Glycyrrhiza root, Cinnamon bark, Ginger in the ratio 7:5:5:3:3:3:3:3:3:2:2:1; reno-protective action against gentamicin nephrotoxicity, possibly through its anti-oxidant action;

Also Known As:

Networked: 81 relevant articles (19 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Takeda, Shuichi: 5 articles (01/2008 - 02/2004)
2.	Ono, Takahiko: 3 articles (01/2011 - 09/2004)
3.	Hattori, Tomohisa: 3 articles (01/2008 - 03/2006)
4.	Kase, Yoshio: 3 articles (01/2008 - 03/2006)
5.	Fujitsuka, Naoki: 2 articles (01/2022 - 02/2004)
6.	Suzuki, Kenji: 2 articles (01/2018 - 05/2007)
7.	Hirako, Shima: 2 articles (11/2017 - 09/2016)
8.	Imai, Kenji: 2 articles (11/2017 - 09/2016)
9.	Kikkawa, Fumitaka: 2 articles (11/2017 - 09/2016)
10.	Kotani, Tomomi: 2 articles (11/2017 - 09/2016)

Related Diseases

1.	Nephrotic Syndrome (Syndrome, Nephrotic) 01/01/1990 - "Although we could consider Sairei-To effective for steroid-dependent nephrotic syndrome in the present study, a larger study is necessary to confirm its efficacy." 01/01/1990 - "Effects of sairei-to on the relapse of steroid-dependent nephrotic syndrome." 01/01/1995 - "37 children with steroid-dependent nephrotic syndrome (SDNS) were administered with Chai-Ling-Tang (Sairei-to) under corticosteroid. " 01/01/1995 - "Therapeutic effect of chai-ling-tang (sairei-to) on the steroid-dependent nephrotic syndrome in children." 01/01/1990 - "Sairei-To (Chai-Ling-Tang) was administered to four patients with steroid-dependent relapsing nephrotic syndrome. "
2.	Fibrosis (Cirrhosis) 11/01/1994 - "A joint multi-institution study was conducted on the efficacy of Sairei-to, centering on urinary tract fibrosis. " 11/01/1994 - "[Clinical efficacy of sairei-to in various urinary tract diseases centering on fibrosis]." 01/01/2016 - "Japanese herbal medicine, Kampo saireito, is used for treatments in patients with digestive diseases, including chronic hepatitis and cirrhosis. " 08/01/2021 - "The herbal medicines Inchinkoto and Saireito improved hepatic fibrosis via aquaporin 9 in the liver of a rat bile duct ligation model." 08/01/2021 - "To determine if the administration of the Japanese herbal medicines Inchinkoto (ICKT) and Saireito (SRT) ameliorate hepatic fibrosis and derangement of hepatocyte aquaporins (AQPs) following bile duct ligation (BDL) in a rat model of obstructive cholestasis. "
3.	Proteinuria 03/01/2007 - "(GTW) and Sairei-to on mesangial damage and proteinuria, and then to clarify the mechanism of these herbs at molecular level by examining the effects on various injurious factors." 07/01/1997 - "The level of proteinuria in the Sairei-to-treated group was significantly lower than that in the PBS treated group. " 03/01/1997 - "TJ-114 prevented proteinuria and histopathological changes in the glomeruli of nephritic rats. " 05/01/1994 - "The effect of Sairei-to on a non-immunological model of proteinuria was also examined. " 05/01/1994 - "For example, 116.6 +/- 89.7 mg/day of proteinuria was observed in control groups compared to 4.2 +/- 15.2 mg/day in the 400 mg/kg BW of Sairei-to treated group 2 days after mAb injection (P < 0.01). "
4.	Glomerulonephritis 01/01/2005 - "Our previous studies have demonstrated that Sairei-to can significantly prevent progression of experimental glomerulonephritis in rats. " 01/01/2005 - "Suppressive mechanisms of Sairei-to on mesangial matrix expansion in rat mesangioproliferative glomerulonephritis." 09/01/2004 - "Suppressive effects of Sairei-to on mesangial proliferation in a rat model of glomerulonephritis." 07/01/1989 - "It has also found that sairei-to has improved proteinurial in minimal change nephrotic syndrome as well as chronic glomerulonephritis in man. " 07/01/1997 - "Suppressive effects of sairei-to on monoclonal antibody 1-22-3-induced glomerulonephritis: analysis of effective components."
5.	Edema (Dropsy) 01/01/2018 - "On the other hand, the postoperative edema in the Saireito group was mostly eliminated at 8 weeks. " 01/01/2018 - "The Effectiveness of Saireito, a Traditional Japanese Herbal Medicine, in Reducing Postoperative Edema after Acquired Ptosis Surgery: A Prospective Controlled Trial." 01/01/2018 - "The computer-based analysis of digital images showed that the edema tended to be reduced in the Saireito group compared with the Control group. " 01/01/2018 - "We focused on the Japanese herbal medicine, Saireito, and evaluated its efficacy in reducing postoperative edema. " 09/01/2007 - "In conclusion, TJ-114 is safe and useful for the prevention and early recovery of postoperative leg edema after THA with an association of rapid CRP reduction."

Related Drugs and Biologics

1.	Plant Extracts
2.	Steroids
3.	Prednisolone (Predate)
4.	Puromycin Aminonucleoside
5.	Diuretics
6.	Aquaporins (Water Channels)
7.	Anticardiolipin Antibodies
8.	Triglycerides (Triacylglycerol)
9.	Puromycin
10.	Calcium

Related Therapies and Procedures

1.	Therapeutics
2.	Kampo Medicine (Kampo)
3.	Oral Administration
4.	Ligation
5.	saiboku-to