N(6)-cyclopentyl-9-methyladenine

selective, orally active A(1) adenosine receptor antagonist

Also Known As:

N 0840; N-0840

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Drug-Related Side Effects and Adverse Reactions 04/01/1993 - "N-0840 (< or = 100 mumol/kg i.v.; < or = 1,000 mumol/kg p.o.) had little or no effect on blood pressure or heart rate and produced no adverse drug reactions.(ABSTRACT TRUNCATED AT 250 WORDS)"
2.	Bradycardia 04/01/1993 - "In anesthetized rats, N-0840 selectively antagonized A1 adenosine receptor-mediated bradycardia, but generally failed to affect A2 adenosine receptor-mediated vasodilation in the in situ perfused hindquarters (A2/A1 selectivity: > or = 33-fold). "

1.	Purinergic P1 Receptors (Adenosine Receptor)