Fc gamma receptor IIA

11/01/2006 - "Multiplex family-based study in systemic lupus erythematosus: association between the R620W polymorphism of PTPN22 and the FcgammaRIIa (CD32A) R131 allele."
01/01/2003 - "[Study of polymorphism of Fc gamma IIa receptors in Chilean patients with systemic lupus erythematosus]."
05/01/2009 - "Meta analysis on the association between FcgammaRIIa-R/H131 polymorphisms and systemic lupus erythematosus."
10/01/2002 - "The classical low-affinity Fcgamma receptor genes (FcgammaRIIA, B, C and FcgammaRIIIA, B) are located on chromosome 1q23, a region that shows strong linkage with human systemic lupus erythematosus (SLE) in several genome-wide scans, and family-based association between FcgammaRIIIA and SLE is now established. "
10/01/2002 - "FcgammaRIIA is a candidate gene involved in the predisposition to systemic lupus erythematosus (SLE). "

04/01/2014 - "Previous studies about the association between the -131R/H polymorphism in the Fc-gamma receptor IIa (FcγRIIa) gene and malaria susceptibility have yielded conflicting results. "
07/01/2007 - "Taken together, our study revealed that the FcgammaRIIa-R/R131 genotype is associated with the development of severe malaria, while the H/H131 genotype is more likely to be associated with mild malaria. "
09/15/2004 - "The present study was undertaken to examine the relationship between Fc gamma RIIa polymorphism and placental malaria (PM) in pregnant women of known human immunodeficiency virus (HIV)-1 status. "
02/01/2015 - "Is Fc gamma receptor IIA (FcγRIIA) polymorphism associated with clinical malaria and Plasmodium falciparum specific antibody levels in children from Burkina Faso?"
04/01/2014 - "Association between Fc-gamma receptor IIa (CD32) gene polymorphism and malaria susceptibility: a meta-analysis based on 6928 subjects."

12/01/2008 - "The results of our study showed that individuals of the FcgammaRIIA genotype seemed to have a poorer prognosis similar to some autoimmune diseases. "
06/01/2004 - "The role of FcgammaRIIA and IIIA polymorphisms in autoimmune diseases."
03/01/2007 - "However, the high degree of homology between FcgammaRIIb and FcgammaRIIa in humans and the lack of specific Abs to differentiate them have hampered study of the normal expression profile of FcgammaRIIb and its potential dysregulation in autoimmune diseases such as systemic lupus erythematosus (SLE). "
10/01/2005 - "The presence of enhanced passive and induced autoimmunity, as well as the emergence of spontaneous autoimmune disease at 20-45 weeks of age, suggest that FcgammaRIIa is a very important factor in the pathogenesis of autoimmune inflammation and a possible target for therapeutic intervention."
08/01/2002 - "In this work we analyse the possible role of polymorphic variants of FcgammaRIIA, FcgammaRIIIA and FcgammaRIIIB genes in the susceptibility to systemic lupus erythematosus, the prototype systemic autoimmune disease. "

05/01/2009 - "Taken together, our study suggests that the FcgammaRIIa-R/H131 polymorphism might contribute to the susceptibility to SLE and lupus nephritis."
06/01/2004 - "The skewed distribution of Fc gamma RIIa genotypes with the predominance of homozygous R/R131 genotype observed in lupus nephritis emphasizes its importance as a heritable risk factor for IC-mediated renal injury in Brazilian lupus patients."
06/01/2004 - "The genotype distribution in lupus nephritis (45% with Fc gamma RIIa-R/R131, 30% with H/R131 and 25% with H/H131) was distinct from that observed in controls (21% with Fc gamma RIIa-R/R131, 52% with H/R131 and 27% with H/H131). "
06/01/2004 - "The Fc gamma RIIa polymorphism has been shown to be associated with lupus nephritis. "
01/01/2003 - "To determine the distribution of Fc gamma RIIA genes in a cohort of Chilean SLE patients, with or without a history of lupus nephritis. "

12/01/2007 - "We found that HIV-infected men in the Multicenter AIDS Cohort Study with the FcgammaRIIa RR genotype progressed to a CD4(+) cell count of <200/mm(3) at a faster rate than individuals with the RH or HH genotypes (relative hazard = 1.6; p = 0.0001). "
12/15/1998 - "The risk of AIDs was strongly associated with variant alleles of MBL (P = 0.01) and weakly associated with an FcgammaRIIa genotype (P = 0.04). "
12/01/2007 - "However, progression to AIDS (using the broad definition of either a CD4(+) cell count <200/mm(3) or development of an AIDS-defining illness) was less impacted by FcgammaRIIa genotype, largely because HH homozygotes had an increased risk of Pneumocystis jiroveci pneumonia as an AIDS-defining illness. "
07/01/2010 - "The Fc Gamma Receptor IIa (FcGRIIa) molecule is involved in the clearance of autoantibodies and a functional single nucleotide polymorphism (SNP), rs1801274, which has been shown to alter autoantibody clearance, has been associated with a number of autoimmune diseases (AIDs) including systemic lupus erythematosus and type 1 diabetes. "