cysteine desulfurase

pyridoxal phosphate enzyme which catalyzes the formation of L-alanine and elemental sulfur from cysteine; required for full activation of the metalloproteins; do not confuse with CsdA protein, E coli

Also Known As:

CsdA desulfurase, E coli; CsdE protein, E coli; iscS protein, E coli

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Sulfur Lyases
      - cysteine desulfurase: 9

Experts

1.	Belaouad, Amine: 1 article (01/2022)
2.	Brunzelle, Joseph S: 1 article (01/2022)
3.	Couture, Jean-François: 1 article (01/2022)
4.	Downs, Diana M: 1 article (01/2022)
5.	Figeys, Daniel: 1 article (01/2022)
6.	Fulton, Ronnie L: 1 article (01/2022)
7.	Giguere, Patrick M: 1 article (01/2022)
8.	Hu, Pei-Shan: 1 article (01/2022)
9.	Irons, Jessica: 1 article (01/2022)
10.	Ju, Huai-Qiang: 1 article (01/2022)

Related Diseases

1.	Benign Familial Pemphigus (Hailey Hailey Disease) 05/01/1969 - "Histochemical study of oxidative enzymes and cysteine desulfurase in familiar benign chronic pemphigus and Darier's disease."
2.	Darier Disease (Darier's Disease) 05/01/1969 - "Histochemical study of oxidative enzymes and cysteine desulfurase in familiar benign chronic pemphigus and Darier's disease."
3.	Starvation 01/01/2021 - "This nanocompartment is upregulated upon sulfate starvation and encapsulates a cysteine desulfurase enzyme via an N-terminal targeting sequence. " 06/11/2013 - "The first step in sulfur mobilization for the biosynthesis of Fe-S clusters under oxidative stress and iron starvation in Escherichia coli involves a cysteine desulfurase SufS. "
4.	Infections 02/25/2015 - "Clinical animals recognized MAP2121c in greater proportion than subclinical and control cows, whereas cysteine desulfurase recognition was not differentiated by infection status. " 05/19/2023 - "Prevalence of mutations in the cysteine desulfurase IscS (Pfnfs1) gene in recurrent Plasmodium falciparum infections following artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) treatment in Matayos, Western Kenya."
5.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2022 - "However, the influence and regulation of cysteine desulfurase (NFS1), a rate-limiting enzyme in iron-sulfur (Fe-S) cluster biogenesis, in colorectal cancer (CRC) remain elusive. "

Related Drugs and Biologics

1.	Enzymes
2.	Sulfur
3.	Iron
4.	Sulfates (Sulfates, Inorganic)
5.	Proteins (Proteins, Gene)
6.	Frataxin
7.	Lumefantrine Drug Combination Artemether (Coartem)
8.	sulofenur (ISCU)
9.	artenimol (dihydroartemisinin)
10.	piperaquine