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SK&F 106610

structure given in first source

Also Known As:

2-(3-(1-piperidinyl)propyl)-8,8-dipropyl-2-azaspiro(4.5)decane dihydrochloride; SK&F 106610 dihydrochloride; SK&F-106610

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - SK&F 106610: 2
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - SK&F 106610: 2
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - SK&F 106610: 2

Related Diseases

1.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/01/1993 - "In this study, we tested the azaspirane, SK&F 106610 in an animal model of autoimmune (type 1) diabetes, the BB rat. " 02/01/1993 - "These results indicate that the azaspirane compound, SK&F 106610 can prevent insulitis and autoimmune diabetes in BB rats and that these actions may be related to the activation of non-specific (natural) suppressor cells."
2.	Inflammation (Inflammations) 02/01/1998 - "SK&F 106615 and SK&F 106610 significantly reduced inflammation in the AA- and PMA-induced inflammation models (p < 0.05) with ED50's of 179 and 120 mg/ear for edema and myeloperoxidase, respectively. "
3.	Edema (Dropsy) 02/01/1998 - "SK&F 106615 and SK&F 106610 significantly reduced inflammation in the AA- and PMA-induced inflammation models (p < 0.05) with ED50's of 179 and 120 mg/ear for edema and myeloperoxidase, respectively. "

Related Drugs and Biologics

1.	azaspirane
2.	Peroxidase (Myeloperoxidase)