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oncopterin
found in urine from patients with solid & blood cancers; structure given in first source
Also Known As:
N(2)-(3-aminopropyl)biopterin; 4(1H)-Pteridinone, 2-((3-aminopropyl)amino)-6-(1,2-dihydroxypropyl)-, (R-(R*,S*))-
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Pteridines: 147
Pterins: 160
Biopterins: 249
oncopterin: 3
Enzymes and Coenzymes: 1
Coenzymes: 558
Biopterins: 249
oncopterin: 3
Related Diseases
1.
Neoplasms (Cancer)
10/06/1995 - "
Our preliminary results indicate that oncopterin could be a most sensitive marker for cancer.
"
03/28/1997 - "
The content of urinary oncopterin from cancer patients is supposed to be very low, with less than 1 mumol/mol creatinine.
"
01/01/1993 - "
Oncopterin may thus be a new biochemical marker of some types of cancer.
"
01/01/1993 - "
The concentrations of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, were determined in urine from various cancer patients by HPLC on a reverse-phase or ion-exchange column.
"
03/28/1997 - "
We previously reported a HPLC assay method using fluorimetric detection for the simultaneous determination of urinary N2-(3-aminopropyl)biopterin (oncopterin, a natural pteridine newly found in urine from cancer patients), biopterin and neopterin.
"
2.
Hematologic Neoplasms (Hematological Malignancy)
01/01/1993 - "
Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers.
"
3.
Stomach Neoplasms (Stomach Cancer)
03/28/1997 - "
Furthermore, oncopterin was not detectable by this HPLC-fluorimetric method in urine samples from patients with stomach cancer who were not treated with methotrexate.
"
03/28/1997 - "
We now have observed that an unknown substance, which may be derived from methotrexate, in urine from a patient with stomach cancer interfered with the assay of oncopterin and demonstrated that oncopterin could be completely separated from the unidentified substance by HPLC using a Nucleosil 100-5SA strong cation-exchange column.
"
Related Drugs and Biologics
1.
Neopterin
2.
Pteridines
3.
Biopterins
4.
Biomarkers (Surrogate Marker)
5.
Pterins
6.
Methotrexate (Mexate)
7.
Creatinine
8.
Cations