thymeleatoxin

causes translocation & down-regulation of multiple protein kinase C isozymes

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Hypoxia (Hypoxemia) 05/01/2001 - "In addition, the PKC activator thymeleatoxin (THX; 10(-7) M) increased pulmonary vascular resistance and compliance in a manner similar to that in hypoxia, and the L-type voltage-dependent Ca(2+) channel blocker nifedipine (10(-6) M) inhibited the response to both THX and hypoxia. " 12/01/2004 - "In separate experiments, pulmonary artery rings were treated with the PKC activator thymeleatoxin for 60 min. After hypoxia, with or without PKC inhibition, or PKC activation alone, pulmonary artery rings were subjected to mRNA analysis for TNF-alpha and IL-1beta via RT-PCR. "
2.	Wounds and Injuries (Trauma) 10/29/2013 - "The wound healed faster in the thymeleatoxin group than in the control group at time points 12, 15, and 20 hours. "

1.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2.	Messenger RNA (mRNA)
3.	Nifedipine (Adalat)