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2,4- (alpha,beta- dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester
structure given in first source; used in neutron capture therapy; selectively localizes in rat 9L gliosarcoma
Also Known As:
2,4-bis(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester; BOPP cpd; Mn-BOPP
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Inorganic Chemicals: 9
Boron Compounds: 91
2,4-(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester: 1
Organic Chemicals: 133
Boron Compounds: 91
2,4-(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Pyrroles: 369
Tetrapyrroles: 70
Porphyrins: 3316
Deuteroporphyrins
2,4-(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester: 1
Fused-Ring Heterocyclic Compounds
4 or More Rings Heterocyclic Compounds
Tetrapyrroles: 70
Porphyrins: 3316
Deuteroporphyrins
2,4-(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester: 1
Polycyclic Compounds: 6
Macrocyclic Compounds: 15
Tetrapyrroles: 70
Porphyrins: 3316
Deuteroporphyrins
2,4-(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester: 1
Biological Factors: 2472
Biological Pigments: 1
Porphyrins: 3316
Deuteroporphyrins
2,4-(alpha,beta-dihydroxyethyl)deuteroporphyrin IX tetrakiscarborane carboxylate ester: 1
Related Diseases
1.
Neoplasms (Cancer)
03/01/1993 - "
Mn-BOPP is unique in that it represents, to the authors' knowledge, the first example of a single agent that can enhance contrast between tumor and normal tissue and be potentially effective as an agent for boron neutron capture therapy.
"
03/01/1993 - "
The results also indicate that Mn-BOPP may have a slower uptake in the 9L glioma than Mn-TPPS4 but a longer retention in the tumor.
"
2.
Glioma (Gliomas)
03/01/1993 - "
The results also indicate that Mn-BOPP may have a slower uptake in the 9L glioma than Mn-TPPS4 but a longer retention in the tumor.
"
Related Drugs and Biologics
1.
manganese(III)tetraphenylporphine sulfonate
Related Therapies and Procedures
1.
Boron Neutron Capture Therapy