3,4-epoxybutane-1,2-diol

a butadiene metabolite

Also Known As:

1,2-dihydroxy-3,4-epoxybutane; 3,4-epoxybutane-1,2-diol, (R*,S*)-isomer; BDO, epoxide; butadiene diolepoxide; butadienediolepoxide; 1,2-Ethanediol, 1-oxiranyl-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - 3,4-epoxybutane-1,2-diol: 2
- Ethers: 242
  - Cyclic Ethers: 12
    - Epoxy Compounds: 689
      - 3,4-epoxybutane-1,2-diol: 2

Experts

1.	Carro, Sujey: 1 article (03/2021)
2.	Gold, Avram: 1 article (03/2021)
3.	Nakamura, Jun: 1 article (03/2021)
4.	Zhang, Zhenfa: 1 article (03/2021)
5.	Blair, I A: 1 article (03/2000)
6.	Chaudhary, A K: 1 article (03/2000)
7.	Kambouris, S: 1 article (03/2000)
8.	Oe, T: 1 article (03/2000)

Related Diseases

Carcinogenesis

03/01/2021 - "We hypothesize that 3,4-epoxybutane-1,2-diol (EBD) may play a critical role in human carcinogenesis due to its high bioavailability. "
03/01/2000 - "This has provided insight into the exposure of the animals to 1,2-epoxy-3-butene (BDO), 1,2,3,4-diepoxybutane (BDO2), and 1,2-dihydroxy-3,4-epoxybutane (BDO-diol), the three oxidative metabolites of BD thought to be responsible for BD-mediated carcinogenesis. "

Related Drugs and Biologics

1.	diepoxybutane