Carthamus tinctorius Honghua extract

neuroprotective extract from the petals of the Chinese safflower (Carthamus tinctorius, Honghua); active principle may be a neutral monosaccharide; crude extract (1gm/ml) contained 149-63 mmol/l glucose

Also Known As:

Networked: 94 relevant articles (13 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Zhu, Yan: 6 articles (01/2020 - 05/2014)
2.	Yang, Jiehong: 4 articles (08/2021 - 06/2014)
3.	Bai, Ji-Qing: 3 articles (01/2022 - 10/2019)
4.	Cao, Jinyi: 3 articles (01/2022 - 09/2014)
5.	Wang, Xiao-Ping: 3 articles (01/2022 - 10/2019)
6.	Yang, Zhifu: 3 articles (01/2022 - 09/2014)
7.	Wan, Haitong: 3 articles (08/2021 - 10/2018)
8.	Duan, Jin-Ao: 3 articles (01/2020 - 12/2013)
9.	Qu, Cheng: 3 articles (01/2020 - 02/2016)
10.	Tang, Yu-Ping: 3 articles (01/2020 - 12/2013)

Related Diseases

1.	Reperfusion Injury 12/01/2021 - "Study on the protective effects of danshen-honghua herb pair (DHHP) on myocardial ischaemia/reperfusion injury (MIRI) and potential mechanisms based on apoptosis and mitochondria." 12/15/2015 - "Hydroxysafflor yellow A (HSYA) is the active component extracted from the Flos Carthami and has been reported to decrease neurological deficit scores following ischemia-reperfusion injury. " 08/29/2022 - "The Danshen-Honghua (DH) herbal pair exhibits a synergistic effect in protecting the cerebrovascular system from ischemia/reperfusion injury, but the therapeutic effect on vascular dementia (VaD) has not been clarified, and the main active ingredient group has not been clarified. " 12/01/2022 - "Mechanism of Huangqi-Honghua combination regulating the gut microbiota to affect bile acid metabolism towards preventing cerebral ischaemia-reperfusion injury in rats." 08/01/2021 - "Compatibility of ingredients of Danshen (Radix Salviae Miltiorrhizae) and Honghua (Flos Carthami) and their protective effects on cerebral ischemia-reperfusion injury in rats."
2.	Brain Ischemia (Cerebral Ischemia) 01/01/2021 - "A Network Pharmacology Approach to Predict the Proangiogenesis Mechanism of Huangqi-Honghua Herb Pair after Cerebral Ischemia." 03/01/2020 - "(CTL, also known as Honghua in China or Safflower) on cerebral ischemia-reperfusion and explored the possible mechanisms on regulating apoptosis and matrix metalloproteinases (MMPs). " 03/01/1997 - "[Effects of flos Carthami on beta-endorphin levels in brain regions of rats with cerebral ischemia]." 12/24/2016 - "Danhong injection (DHI) is a standardized product extracted from Radix et Rhizoma Salviae Miltiorrhizae and Flos Carthami , which has been long applied mainly used to treat ischemic encephalopathy and cardiac diseases including myocardial infarction and angina in clinical practice. " 08/01/2021 - "Compatibility of ingredients of Danshen (Radix Salviae Miltiorrhizae) and Honghua (Flos Carthami) and their protective effects on cerebral ischemia-reperfusion injury in rats."
3.	Stroke (Strokes) 01/01/2019 - "(Honghua) is an effective treatment for stroke. " 12/29/2017 - "In China, combination of herb Danshen (Salvia miltiorrhiza Bge) and Honghua (Carthamus tinctorius L.) is effective for stroke treatment in patients but its underlying mechanism requires further investigation. " 11/13/2017 - "A compound-target-disease & function-pathway network was constructed and analyzed, indicating that 37 ingredients derived from DH (Salvia miltiorrhiza Bge., Flos Carthami tinctorii and DHI) modulated 68 common targets shared by stroke and CAD. " 02/01/2016 - "These results suggested that Salviae Miltiorrhizae Radix et Rhizoma, Carthami Flos is often combined with herbs for activating blood and promoting circulation of qi to treat gynecopathy, stasis blood pain syndrome, stroke and other syndromes." 09/11/2014 - "(Honghua) has been extensively used as traditional herb medicine in China for the treatment of stroke and myocardial ischemia diseases with Qi deficiency and blood stasis (QDBS) syndrome. "
4.	Coronary Disease (Coronary Heart Disease) 01/01/2022 - "Honghua injection combined with western medicine is more effective than western medicine alone in patients with coronary heart disease angina pectoris. " 01/01/2022 - "Computer extensively searched PubMed, Cochrane Library, Embase, China Biomedical Archives (SinoMed), China Knowledge Network (CNKI), Chinese Journal Full-text Database (VIP), Wanfang Data Knowledge Service Platform (Wanfang), and collected randomized controlled trials (RCTs) of honghua injection combined with western medicine in the treatment of coronary heart disease angina pectoris. " 01/01/2022 - "To evaluate the effectiveness of honghua injection combined with western medicine in the treatment of coronary heart disease angina pectoris. " 01/01/2022 - "Meta-Analysis of the Effect of Honghua Injection in the Treatment of Coronary Heart Disease Angina Pectoris." 05/01/2014 - "Danhong injection (DHI), a certificated Chinese medical product made from radix salviae miltiorrhizae and flos carthami, is prescribed to patients with coronary heart disease in China. "
5.	Ischemic Stroke 12/10/2021 - "To explore the Radix Paeoniae Rubra-Flos Carthami herb pair's (RPR-FC) potential mechanism in treating ischemic stroke (IS) by network pharmacology and molecular docking technology.The" 12/10/2021 - "To explore the Radix Paeoniae Rubra-Flos Carthami herb pair's potential mechanism in the treatment of ischemic stroke by network pharmacology and molecular docking technology." 01/01/2022 - "Comparative efficacy of Honghua class injections for treating acute ischemic stroke: A Bayesian network meta-analysis of randomized controlled trials." 12/01/2022 - "The objective of this study is to elucidate the mechanism underlying Huangqi-Honghua (HQ-HH) for the treatment of ischaemic stroke by gut microbiota analysis and metabonomics. " 08/01/2014 - "Danhong injection (DHI), a Chinese Materia Medica standardized product extracted from Radix Salviae miltiorrhizae and Flos Carthami tinctorii, is widely used in China for treating acute ischemic stroke. "

Related Drugs and Biologics

1.	Carthamus tinctorius Honghua extract
2.	danhong
3.	aceglutamide
4.	acceleratory factor from growth hormone (AcG)
5.	salicylhydroxamic acid (SHAM)
6.	Materia Medica (Homeopathic Remedies)
7.	Huang Qi
8.	buyang huanwu
9.	Retinaldehyde (Retinal)
10.	shenkang

Related Therapies and Procedures

1.	Injections
2.	Chinese Traditional Medicine (Traditional Chinese Medicine)
3.	Meridians (Jing Luo)
4.	Trabeculectomy (Trabeculoplasty)
5.	Therapeutics