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6-chloropurine

metabolized to form 6-mercaptopurine

Networked: 17 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - 6-chloropurine: 17

Experts

1.	Gabelica Marković, Vesna: 1 article (03/2020)
2.	Grbčić, Petra: 1 article (03/2020)
3.	Jadreško, Dijana: 1 article (03/2020)
4.	Kraljević Pavelić, Sandra: 1 article (03/2020)
5.	Mišetić, Petra: 1 article (03/2020)
6.	Padovan, Jasna: 1 article (03/2020)
7.	Pavelić, Krešimir: 1 article (03/2020)
8.	Piškor, Martina: 1 article (03/2020)
9.	Raić-Malić, Silvana: 1 article (03/2020)
10.	Rep, Valentina: 1 article (03/2020)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1993 - "6-Chloropurine (CP) has antitumor activity against animal and human neoplasms, but the mechanism is unclear. " 08/01/1963 - "SOME FACTORS AFFECTING THE TUMOR-INHIBITORY PROPERTIES OF COMBINATIONS OF AZASERINE AND 6-CHLOROPURINE." 01/18/1966 - "Conversion of 6-chloropurine to its ribonucleotide by ascites tumor cells." 01/01/2016 - "Among the investigated compounds, ribonucleosides containing 6-chloropurine (3), 7-guanine (5) and a pyrrolopyrimidine (18) as nucleobases, show promising anti-glioma activity with good selectivity indices, and can be considered as lead structures for further anti-cancer studies."
2.	Disease Progression 04/21/2014 - "Pursuing our studies on selective BChE inhibitors, that may contribute to understand the role of this enzyme in disease progression, we present now microwave-assisted synthesis and anticholinesterase activity of a new nucleoside series embodying 6-chloropurine or 2-acetamido-6-chloropurine linked to D-glucosyl, D-galactosyl and D-mannosyl residues. "
3.	Glioma (Gliomas) 01/01/2016 - "Among the investigated compounds, ribonucleosides containing 6-chloropurine (3), 7-guanine (5) and a pyrrolopyrimidine (18) as nucleobases, show promising anti-glioma activity with good selectivity indices, and can be considered as lead structures for further anti-cancer studies."
4.	Ascites 10/01/1961 - "Comparative studies on the in vivo action of 6-chloropurine, 6-chloropurine ribonucleoside, and 6-chloro-9-ethylpurine on sarcoma 180 ascites cells." 01/18/1966 - "Conversion of 6-chloropurine to its ribonucleotide by ascites tumor cells." 11/01/1960 - "Inhibition of the biosynthesis of purines de novo by 6-chloropurine and azaserine in sensitive and naturally resistant ascites cells."
5.	Sarcoma 180 10/01/1961 - "Comparative studies on the in vivo action of 6-chloropurine, 6-chloropurine ribonucleoside, and 6-chloro-9-ethylpurine on sarcoma 180 ascites cells." 11/01/1960 - "Utilization of preformed purines by sarcoma 180 or hepatoma 134 cells treated with 6-chloropurine or a combination of 6-chloropurine and azaserine."

Related Drugs and Biologics

1.	Ribonucleosides
2.	Nucleosides
3.	Enzymes
4.	Cholinesterase Inhibitors (Anticholinesterases)
5.	pyrrolopyrimidine
6.	Purines
7.	Azaserine
8.	Mercaptopurine (6 Mercaptopurine)
9.	Thioguanine (Tioguanine)
10.	Ribonucleotides

Related Therapies and Procedures

1.	Cardiopulmonary Resuscitation (CPR)