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RA X peptide

bicyclic hexapeptides; structure given in first source

Also Known As:

RA-X

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - RA X peptide: 3
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - RA X peptide: 3

Experts

1.	Callado, Maria Roseli Monteiro: 1 article (01/2011)
2.	Lima, José Rubens Costa: 1 article (01/2011)
3.	Nobre, Christiane Aguiar: 1 article (01/2011)
4.	Vieira, Walber Pinto: 1 article (01/2011)

Related Diseases

1.	Psoriatic Arthritis 01/01/2011 - "In the infliximab group, subdivided according to pathologies [rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PA)], different reactivity rates were observed, the lowest value occurring among RA patients: (RA x AS: OR = 0.13; CI: 0.03-0.47; χ ² = 12; P = 0.0004) and (RA x PA: OR = 0.16; CI: 0.02-1.04; χ² Yates corrected = 3.6; P = 0.05). "
2.	Ankylosing Spondylitis 01/01/2011 - "In the infliximab group, subdivided according to pathologies [rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PA)], different reactivity rates were observed, the lowest value occurring among RA patients: (RA x AS: OR = 0.13; CI: 0.03-0.47; χ ² = 12; P = 0.0004) and (RA x PA: OR = 0.16; CI: 0.02-1.04; χ² Yates corrected = 3.6; P = 0.05). "
3.	Leukemia P388 08/01/1993 - "A number of RA-VII derivatives having various amino acids including proline (6), pipecolic acid (11), norvaline (12), ornithine (14), aspartic acid (15) and methionine (20) in place of Ala2 have been synthesized from RA-X methyl ester (3) and evaluated for cytotoxicity to P388 leukemia and KB cells in vitro. "
4.	Infarction (Infarctions) 01/01/1994 - "Infarct size, measured by triphenyltetrazolium staining, was markedly reduced in lazaroid-treated rats as compared with controls (6.0 +/- 1.5 vs. 22.2 +/- 3.9%, p = 0.001, infarct size/ischemic RA x 100). "
5.	Rheumatoid Arthritis 01/01/2011 - "In the infliximab group, subdivided according to pathologies [rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PA)], different reactivity rates were observed, the lowest value occurring among RA patients: (RA x AS: OR = 0.13; CI: 0.03-0.47; χ ² = 12; P = 0.0004) and (RA x PA: OR = 0.16; CI: 0.02-1.04; χ² Yates corrected = 3.6; P = 0.05). "

Related Drugs and Biologics

1.	Proline (L-Proline)
2.	Ornithine
3.	Methionine (L-Methionine)
4.	Esters
5.	Aspartic Acid (Aspartate)
6.	Amino Acids
7.	Infliximab (Remicade)
8.	RA VII
9.	pipecolic acid
10.	triphenyltetrazolium