U 80816B

cholinergic direct agonist; U-80816E is the oxalate salt

Also Known As:

1-(4-(5-methyl-1H-imidazol-1-yl)-2-butynyl)-2-pyrrolidinone hydrobromide; U 80816E; U-80816B; U-80816E; U80816B; U80816E; 2-Pyrrolidinone, 1-(4-(5-methyl-1H-imidazol-1-yl)-2-butynyl)-, monohydrobromide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Oxotremorine: 288
        U 80816B: 1

Related Diseases

Ischemia

05/01/1993 - "dose of U-80816E was found to produce a 1.0 degree C decrease in brain temperature (measured with a tympanic temperature probe) at 10 minutes of ischemia compared with that of saline-treated gerbils. "
05/01/1993 - "The novel muscarinic cholinergic partial agonist U-80816E was tested in the gerbil brief bilateral carotid occlusion ischemia model based on the rationale that the compound's hypothermic properties might afford effective protection of the selectively vulnerable hippocampal CA1 region. "

Related Drugs and Biologics

1.	Cholinergic Agents (Cholinergics)
2.	Dihydrotachysterol (AT 10)