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technetium Tc 99m 1,2- bis(bis(2- ethoxyethyl)phosphino)ethane (Myoview)

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Also Known As:

Myoview; 99mTc-tetrafosmin; 99mTc-tetrofosmin; Amersham brand of technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane; Nycomed brand of technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane; Tc-99m-PPN1011; Tc-99m-tetrofosmin; technetium-99m-tetrofosmin

Networked: 269 relevant articles (11 outcomes, 46 trials/studies)

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Drug Context: Research Results

Experts

1.	Alexiou, George A: 11 articles (06/2012 - 12/2007)
2.	Tsiouris, Spyridon: 11 articles (06/2012 - 12/2007)
3.	Kyritsis, Athanasios P: 11 articles (06/2012 - 12/2007)
4.	Fotopoulos, Andreas D: 11 articles (06/2012 - 12/2007)
5.	Polyzoidis, Konstantinos S: 8 articles (07/2009 - 12/2007)
6.	Matsubara, Hiroaki: 7 articles (01/2013 - 11/2004)
7.	Madeddu, Giuseppe: 7 articles (11/2011 - 10/2002)
8.	Spanu, Angela: 7 articles (11/2011 - 10/2002)
9.	Azuma, Akihiro: 7 articles (09/2008 - 02/2003)
10.	Sugihara, Hiroki: 7 articles (09/2008 - 12/2002)

Related Diseases

1.	Coronary Artery Disease (Coronary Atherosclerosis) 09/01/1995 - "The aim of this study was to determine whether the diagnosis for coronary artery disease (CAD) with 99mTc-tetrofosmin (Tf) myocardial scintigraphy was improved by the combination of function image and perfusion image as compared with perfusion alone. " 06/01/2003 - "In order to evaluate the diagnostic efficacy of the 1-day separate acquisition dual-isotope single-photon emission computed tomography (SPECT) protocol, using 201Tl for the rest and 99mTc-tetrofosmin for the stress images, a consecutive series of patients with suspected or known coronary artery disease (CAD) was studied that also underwent coronary angiography. " 02/01/2008 - "The aim of this study was to evaluate the accuracy of 1-day DypEX 99mTc-tetrofosmin tomography in the identification and localization of culprit lesion in the patients with known coronary artery disease (CAD). " 03/01/1999 - "This study shows that 99mTc-tetrofosmin SPECT is accurate in the detection of coronary artery disease. " 03/01/1999 - "The study group consisted of 235 consecutive patients, 204 (87%) of whom were men, with a mean age of 57+/-10 years, and with suspected or known coronary artery disease, who underwent 99mTc-tetrofosmin SPECT and coronary angiography. "
2.	Breast Neoplasms (Breast Cancer) 05/01/1996 - "We conclude that 99mTc-tetrofosmin scintigraphy is helpful for evaluating breast cancer." 11/01/1997 - "In the following mammography, disseminated micro calcifications were found in the left breast and a 99mTc-tetrofosmin study was performed for detection of breast cancer. " 01/01/2006 - "Technetium-99m-tetrofosmin in diagnosis of breast cancer and axillary lymph node involvement." 01/01/2003 - "Technetium-99m-tetrofosmin myocardial imaging in cardiotoxicity screening for left-sided breast cancer irradiation." 12/01/2001 - "99mTc-Tetrofosmin pinhole-SPECT (P-SPECT) and radioguided sentinel node (SN) biopsy and in breast cancer axillary lymph node staging."
3.	Myocardial Infarction 06/01/1995 - "These results demonstrate that quantitative analysis of resting 99mTc-tetrofosmin regional uptake detects the majority of segments supplied by occluded coronary arteries with poor collateral flow and suggest that this tracer may be helpful in the diagnosis of acute myocardial infarction." 01/01/2006 - "Prognostic implications of a normal stress technetium-99m-tetrofosmin myocardial perfusion study in patients with a healed myocardial infarct and/or previous coronary revascularization." 12/01/2009 - "The relationship between reverse redistribution of 99mTc-tetrofosmin in sub-acute phase and left ventricular functional recovery in chronic phase in patients with acute myocardial infarction." 08/01/2006 - "Comparative assessment of 18F-fluorodeoxyglucose PET and 99mTc-tetrofosmin SPECT for the prediction of functional recovery in patients with reperfused acute myocardial infarction." 03/01/2006 - "[Effect of collateral circulation on myocardial protection in patients with acute myocardial infarction: comparison of technetium-99m-tetrofosmin myocardial single photon emission computed tomography and coronary angiography]."
4.	Neoplasms (Cancer) 09/01/2013 - "The aim of our study was to investigate the role of technetium-99m-tetrofosmin (99mTc-TF) as a functional imaging agent reflecting Pgp expression in these tumors. " 09/01/2003 - "The aim of our study was to investigate the role of 99mTc-tetrofosmin as a functional imaging agent reflecting Pgp expression in these tumors. " 05/01/1996 - "Tc-99m-tetrofosmin may be used for tumor imaging though more studies are required to evaluate diagnostic accuracy and the significance of delayed images." 01/01/2014 - "Cardiac myoview tests done at baseline and 1-year follow-up for 15 out of 18 left sided breast cancers did not show any abnormalities related to radiation. " 04/01/2009 - "Intracranial tumors after radiation therapy: role of 99mTc-tetrofosmin SPECT/CT with a hybrid camera."
5.	Neoplasm Metastasis (Metastasis) 09/01/2002 - "All patients underwent whole body planar examination after administration of 500-550 MBq Tc-99m-tetrofosmin, and in case of lung metastases on CT scan, SPECT images were carried out. " 03/15/2002 - "99mTC-tetrofosmin scan correctly detected most skeleton (9 of 10) and brain (5 of 7) metastases. " 01/01/2000 - "After administration of about 600 MBq Tc-99m-tetrofosmin dynamic images up to 10 min were performed in 7 patients (1 image per 10 sec) to evaluate the optimal tracer uptake in the metastases. " 11/01/1998 - "The sensitivities of 201Tl, 99mTc-tetrofosmin and 131I in diagnosing distant metastases were comparable (0.85, 0.85 and 0.78, respectively). " 05/01/1998 - "One liver metastasis could not be detected because of the physiologic tracer distribution of 99mTc-tetrofosmin. "

Related Drugs and Biologics

1.	Technetium Tc 99m Sestamibi (Cardiolite)
2.	Adenosine
3.	P-Glycoprotein
4.	Dipyridamole (Persantine)
5.	Nitroglycerin (Dynamite)
6.	technetium Tc 99m 1,2- bis(bis(2- ethoxyethyl)phosphino)ethane (Myoview)
7.	Dobutamine
8.	Hormones
9.	Multidrug Resistance-Associated Proteins
10.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Gamma Cameras (Gamma Camera)
3.	Thyroidectomy
4.	Neoadjuvant Therapy
5.	Myocardial Revascularization