technetium tc-99m tetrofosmin (Myoview)

Also Known As:

Myoview; 99mTc-tetrafosmin; 99mTc-tetrofosmin; PPN-1011; PPN1011; Tc-99m-PPN1011; Tc-99m-tetrofosmin; technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane; technetium(1+)-99tc, bis(6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane-.kappa.p,.kappa.p')dioxo-, (oc-6-11)-; technetium-99m-tetrofosmin

Networked: 315 relevant articles (14 outcomes, 57 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - technetium tc-99m tetrofosmin: 315
- Organometallic Compounds: 64
  - Organotechnetium Compounds: 1
    - technetium tc-99m tetrofosmin: 315

Experts

1.	Alexiou, George A: 12 articles (01/2017 - 12/2007)
2.	Fotopoulos, Andreas D: 12 articles (01/2017 - 12/2007)
3.	Kyritsis, Athanasios P: 12 articles (01/2017 - 12/2007)
4.	Tsiouris, Spyridon: 11 articles (06/2012 - 12/2007)
5.	Matsubara, Hiroaki: 8 articles (01/2013 - 11/2004)
6.	Polyzoidis, Konstantinos S: 8 articles (07/2009 - 12/2007)
7.	Azuma, Akihiro: 8 articles (09/2008 - 05/2002)
8.	Sugihara, Hiroki: 8 articles (09/2008 - 05/2002)
9.	Madeddu, Giuseppe: 7 articles (11/2011 - 10/2002)
10.	Spanu, Angela: 7 articles (11/2011 - 10/2002)

Related Diseases

1.	Myocardial Infarction 06/01/1995 - "These results demonstrate that quantitative analysis of resting 99mTc-tetrofosmin regional uptake detects the majority of segments supplied by occluded coronary arteries with poor collateral flow and suggest that this tracer may be helpful in the diagnosis of acute myocardial infarction." 01/01/2006 - "Prognostic implications of a normal stress technetium-99m-tetrofosmin myocardial perfusion study in patients with a healed myocardial infarct and/or previous coronary revascularization." 12/01/2009 - "The relationship between reverse redistribution of 99mTc-tetrofosmin in sub-acute phase and left ventricular functional recovery in chronic phase in patients with acute myocardial infarction." 08/01/2006 - "Comparative assessment of 18F-fluorodeoxyglucose PET and 99mTc-tetrofosmin SPECT for the prediction of functional recovery in patients with reperfused acute myocardial infarction." 03/01/2006 - "[Effect of collateral circulation on myocardial protection in patients with acute myocardial infarction: comparison of technetium-99m-tetrofosmin myocardial single photon emission computed tomography and coronary angiography]."
2.	Coronary Artery Disease (Coronary Atherosclerosis) 09/01/1995 - "The aim of this study was to determine whether the diagnosis for coronary artery disease (CAD) with 99mTc-tetrofosmin (Tf) myocardial scintigraphy was improved by the combination of function image and perfusion image as compared with perfusion alone. " 06/16/2021 - "The aim of this experimental study is to assess quantitative accuracy and precision of a novel iterative reconstruction technique (Evolution; GE Healthcare) for the potential application of response monitoring using 99mTc-tetrofosmin SPECT/CT in patients with coronary artery disease (CAD). " 02/01/2008 - "The aim of this study was to evaluate the accuracy of 1-day DypEX 99mTc-tetrofosmin tomography in the identification and localization of culprit lesion in the patients with known coronary artery disease (CAD). " 03/01/1999 - "This study shows that 99mTc-tetrofosmin SPECT is accurate in the detection of coronary artery disease. " 03/01/1999 - "The study group consisted of 235 consecutive patients, 204 (87%) of whom were men, with a mean age of 57+/-10 years, and with suspected or known coronary artery disease, who underwent 99mTc-tetrofosmin SPECT and coronary angiography. "
3.	Breast Neoplasms (Breast Cancer) 05/01/1996 - "We conclude that 99mTc-tetrofosmin scintigraphy is helpful for evaluating breast cancer." 10/01/2002 - "The aim of this study was to evaluate the usefulness of supine 99mTc-tetrofosmin SPECT in the detection of small size breast carcinomas (BC), for which planar scintimammography has showed a low sensitivity. " 01/01/2000 - "Since the comparative value of several nuclear medicine investigations for breast cancer has not been established, the rationale of this study was to examine the diagnostic performances of F-18-fluorodeoxyglucose (FDG) and Tc-99m-tetrofosmin both in single photon emission computed tomography (SPECT) and planar technique in an intraindividual comparative study.A total of 54 patients with suspected breast cancer (48 malignant and 9 benign lesions) was investigated by planar and SPECT imaging with both FDG and tetrofosmin within the last preoperative week. " 11/01/1997 - "In the following mammography, disseminated micro calcifications were found in the left breast and a 99mTc-tetrofosmin study was performed for detection of breast cancer. " 01/01/2006 - "Technetium-99m-tetrofosmin in diagnosis of breast cancer and axillary lymph node involvement."
4.	Neoplasms (Cancer) 09/01/2013 - "The aim of our study was to investigate the role of technetium-99m-tetrofosmin (99mTc-TF) as a functional imaging agent reflecting Pgp expression in these tumors. " 09/01/2003 - "The aim of our study was to investigate the role of 99mTc-tetrofosmin as a functional imaging agent reflecting Pgp expression in these tumors. " 05/01/1996 - "Tc-99m-tetrofosmin may be used for tumor imaging though more studies are required to evaluate diagnostic accuracy and the significance of delayed images." 11/29/2018 - "Different Efflux Transporter Affinity and Metabolism of 99mTc-2-Methoxyisobutylisonitrile and 99mTc-Tetrofosmin for Multidrug Resistance Monitoring in Cancer." 11/01/2008 - "With 99mTc-tetrofosmin a large variety of different unknown tumors can be detected during MPS."
5.	Neoplasm Metastasis (Metastasis) 09/01/2002 - "All patients underwent whole body planar examination after administration of 500-550 MBq Tc-99m-tetrofosmin, and in case of lung metastases on CT scan, SPECT images were carried out. " 03/15/2002 - "99mTC-tetrofosmin scan correctly detected most skeleton (9 of 10) and brain (5 of 7) metastases. " 01/01/2000 - "After administration of about 600 MBq Tc-99m-tetrofosmin dynamic images up to 10 min were performed in 7 patients (1 image per 10 sec) to evaluate the optimal tracer uptake in the metastases. " 11/01/1998 - "The sensitivities of 201Tl, 99mTc-tetrofosmin and 131I in diagnosing distant metastases were comparable (0.85, 0.85 and 0.78, respectively). " 05/01/1998 - "One liver metastasis could not be detected because of the physiologic tracer distribution of 99mTc-tetrofosmin. "

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Related Therapies and Procedures

1.	Cell- and Tissue-Based Therapy (Cell Therapy)
2.	Microspheres (Microsphere)
3.	Gamma Cameras (Gamma Camera)
4.	Neoadjuvant Therapy
5.	Myocardial Revascularization