RP 58802B

RN given refers to parent cpd without isomeric designation; RP 58802B is the di-HCl; structure given in first source

Also Known As:

RP 58802B dihydrochloride; RP 58802B, (R*,R*)-(+-)-isomer; RP 58802B, (R*,S*)-(+-)-isomer; RP 58802B, (R-(R*,R*))-isomer; RP 58802B, (R-(R*,S*))-isomer; RP 58802B, (S-(R*,R*))-isomer; RP 58802B, (S-(R*,S*))-isomer; RP-58802B

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Bronchial Hyperreactivity 09/01/1992 - "Although PAF-induced bronchial hyperreactivity was not accompanied by an increase in the number of pulmonary eosinophils, RP 58802B (25 mg/kg p.o.) reduced the numbers of eosinophils recovered by lavage. " 09/01/1992 - "These data suggest that RP 58802B, in addition to being a potent and long acting bronchodilator, may have a prophylactic role in preventing bronchial hyperreactivity and in reducing plasma exudation into the lungs." 09/01/1992 - "We have also examined the effects of RP 58802B on airway reactivity and inflammatory cell infiltration in platelet-activating factor (PAF) (aerosol)-induced bronchial hyperreactivity and on PAF (tracheal instillation)-induced microvascular leakage in the guinea-pig. "
2.	Bronchial Spasm 09/01/1992 - "Nebulized RP 58802B produced a rapid onset and long lasting inhibition of histamine-induced bronchospasm in the anaesthetized guinea-pig (EC50 = 3.2 +/- 0.9 micrograms/ml; duration greater than 90 min). " 09/01/1992 - "We have examined the protective actions of RP 58802B, a novel beta 2-adrenoceptor agonist, administered by the inhaled and oral routes in the anaesthetized and conscious guinea-pig against bronchospasm induced by histamine or antigen (ovalbumin). "

Related Drugs and Biologics

1.	Platelet Activating Factor
2.	Ovalbumin
3.	Histamine (Histamine Dihydrochloride)
4.	Bronchodilator Agents (Bronchodilators)
5.	Antigens
6.	Aerosols