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Y 26611

Also Known As:

Y-26611

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        Y 26611: 4

Related Diseases

1.	Phototoxic Dermatitis (Phototoxicity) 04/01/1994 - "UV-dependent quinolone-induced human erythrocyte membrane lipid peroxidation: studies on the phototoxicity of Y-26611, a new quinolone derivative." 04/01/1994 - "Using lipid peroxidation as an index of phototoxicity, we studied the effects of a new quinolone derivative, Y-26611 together with ofloxacin, sparofloxicin and lomefloxacin on washed human erythrocyte suspensions. "
2.	Photosensitivity Disorders (Photodermatitis) 05/01/1995 - "Under anaesthesia, the hair on the dorsal side of rats was shaved, then a fluoroquinolone derivative, Y-26611 or ofloxacin was administered subcutaneously (SC) followed by irradiation of a 3 cm diameter circular area of the skin with UV-B(ultraviolet-B) for 45 min. Peak photodermatitis was observed 24 h after irradiation in Y-2611-treated skin. "
3.	Infections 07/01/1992 - "fortuitum-infected (iv) A/J mice were treated with Y-26611 by gavage at doses of 0.5-2 mg/mouse, once daily, six times per week, from day 1 for up to 4 weeks after infection, mice were protected from death and the number of CFU recovered from their visceral organs, such as the lungs, spleen and kidneys were reduced. "
4.	Erythema 05/01/1998 - "After confirming that the C* value increased in an irradiation dose-dependent manner and reached a plateau 1-2 h after irradiation of UVB alone or UVA coadministered with an FQ, Y-26611 (10 mg/kg, i.p.), guinea pigs were pretreated with indomethacin, butylated hydroxytoluene (BHT) or beta-carotene before, or treated with H1- or H2-receptor antagonist, superoxide dismutase or N omega-nitro-L- arginine methyl ester after UV irradiation, and their inhibitory effects against erythema were evaluated. "

Related Drugs and Biologics

1.	Quinolones
2.	Ofloxacin (Ofloxacine)
3.	Fluoroquinolones
4.	NG-Nitroarginine Methyl Ester (L-NAME)
5.	beta Carotene (Betacarotene)
6.	Suspensions
7.	Superoxide Dismutase
8.	Indomethacin (Indometacin)
9.	Butylated Hydroxytoluene (BHT)
10.	lomefloxacin (Maxaquin)