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calotroposide A

structure given in first source; oxypregnane-oligoglycoside from the root of Calotropis gigantea

Also Known As:

12-O-benzoyllineolon 3-O-cymaropyranosyl-1-4-oleandropyranosyl-1-4-oleandropyranosyl-1-4-cymaropyranosyl-1-4-cymaropyranoside

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - calotroposide A: 1
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - calotroposide A: 1

Experts

1.	Mutiah, Roihatul: 1 article (06/2018)
2.	Sukardiman, Sukardiman: 1 article (06/2018)
3.	Widyawaruyanti, Aty: 1 article (06/2018)

Related Diseases

1.

Colonic Neoplasms (Colon Cancer)

06/25/2018 - "Conclusion: Calotroposide A induces anticancer activity against WiDr colon cancer cells by means of apoptosis induction mechanism through extrinsic pathway with increased expression of caspase-8."
06/25/2018 - "Calotroposide A is capable of inhibiting the growth of WiDr colon cancer cells at IC50 17.23μg/ml. Cell apoptosis induction took place and was indicated by cell apoptosis increase, S and G2/M accumulation and by caspase-8 expression. "

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