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3- carbamoyl- 2,2,5,5- tetramethyl- 1- pyrrolidinyl- N- oxyl

structure given in first source

Also Known As:

3-carbamoyl-proxyl; N-3-carbamoyl-2,2,5,5-tetramethylpyrrolidin-1-yloxyl

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - 3-carbamoyl-2,2,5,5-tetramethyl-1-pyrrolidinyl-N-oxyl: 4
- Heterocyclic Oxides
  - Cyclic N-Oxides: 3
    - 3-carbamoyl-2,2,5,5-tetramethyl-1-pyrrolidinyl-N-oxyl: 4

Experts

1.	Assayag, Miri: 2 articles (01/2021 - 10/2015)
2.	Berkman, Neville: 2 articles (01/2021 - 10/2015)
3.	Goldstein, Sara: 2 articles (01/2021 - 10/2015)
4.	Samuni, Amram: 2 articles (01/2021 - 10/2015)
5.	Hu, Guohan: 1 article (02/2003)
6.	Lyeth, Bruce G: 1 article (02/2003)
7.	Mitchell, James B: 1 article (02/2003)
8.	Watson, Joe C: 1 article (02/2003)
9.	Zhao, Xueren: 1 article (02/2003)

Related Diseases

1.	Asthma (Bronchial Asthma) 10/01/2015 - "The present study investigated the effect of 4-hydroxy-2,2,6,6-tetramethyl-piperidine-N-oxyl (TPL) and 3-carbamoyl-proxyl (3-CP) in a mouse model of ovalbumin (OVA)-induced allergic asthma. " 01/01/2021 - "We have recently demonstrated that nitroxides, particularly 3-carbamoyl-proxyl (3-CP), markedly reduce airway inflammation, airway hyper-responsiveness, and protein nitration of the lung tissue in a mouse model of ovalbumin-induced acute asthma, thus prompting its use for the treatment of IPF. "
2.	Hypotension (Low Blood Pressure) 02/01/2003 - "Of the nitroxides, 3-carbamoyl-proxyl (3-CP) is especially promising for clinical use, because it does not cause hypotension in animals. " 11/01/1998 - "In vivo radioprotection for all of the compounds except 3-carbamoyl-PROXYL may be at least partially explained by the induction of hypotension and bone marrow hypoxia. "
3.	Respiratory Hypersensitivity 01/01/2021 - "We have recently demonstrated that nitroxides, particularly 3-carbamoyl-proxyl (3-CP), markedly reduce airway inflammation, airway hyper-responsiveness, and protein nitration of the lung tissue in a mouse model of ovalbumin-induced acute asthma, thus prompting its use for the treatment of IPF. "
4.	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/01/2021 - "3-Carbamoyl-proxyl nitroxide radicals attenuate bleomycin-induced pulmonary fibrosis in mice."
5.	Ischemia 02/01/2003 - "Neuroprotection by the stable nitroxide 3-carbamoyl-proxyl during reperfusion in a rat model of transient focal ischemia."

Related Drugs and Biologics

1.	Ovalbumin
2.	nitroxyl
3.	Proteins (Proteins, Gene)
4.	Bleomycin (Blenoxane)