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unglycosylated rt-PA

unglycosylated recombinant tissue-type plasminogen activator

Also Known As:

BM 06.021; BM-06.021; unglycosylated recombinant tissue-type plasminogen activator

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.

Thrombosis (Thrombus)

07/01/1992 - "The thrombolytic effects after intravenous bolus injection of 200 kU/kg BM 06.021 were investigated in a canine model of coronary artery thrombosis. "
07/01/1992 - "The residual thrombus wet weight did not significantly differ between BM 06.021 and alteplase (5.7 +/- 1.8 vs. 6.3 +/- 1.1 mg). "
07/01/1992 - "The dose-response curve of BM 06.021 for thrombolysis in a rabbit model of jugular vein thrombosis was located to the left of that for alteplase with a 2.1-fold lower effective dose of 50% thrombolysis (ED50) of BM 06.021 (207 vs. 436 kU/kg). "
07/01/1992 - "Intravenous bolus injection of 200 kU/kg BM 06.021 induced the same reperfusion rate (4/6) as intravenous infusion of 800 kU/kg alteplase over 90 min in a canine model of coronary artery thrombosis. "

Related Drugs and Biologics

1.	Tissue Plasminogen Activator (Alteplase)

Related Therapies and Procedures

1.	Intravenous Infusions