theaflavin digallate

structure given in first source; prophylactic agent against pertussis infection

Also Known As:

1,8-bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one digallate; teaflavin digallate; Benzoic acid, 3,4,5-trimethoxy-, diester with 1,8-bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Jankun, Jerzy: 1 article (07/2010)
2.	Skrzypczak-Jankun, Ewa: 1 article (07/2010)

Related Diseases

1.	Lewis Lung Carcinoma 09/01/1997 - "Theaflavin and theaflavin digallate, which are components of black tea were examined by in vitro invasion assay with mouse Lewis lung carcinoma LL2-Lu3 cells, which are highly metastatic. "
2.	Stomach Neoplasms (Stomach Cancer) 04/01/1998 - "The exposure of human stomach cancer KATO III cells to black tea theaflavin extract, free theaflavin, and theaflavin digallate that are main components of the extract, led to both growth inhibition and the induction of programmed cell death (apoptosis). "
3.	Obesity 07/01/2010 - "Theaflavin digallate inactivates plasminogen activator inhibitor: could tea help in Alzheimer's disease and obesity?"
4.	Neoplasms (Cancer) 09/01/1997 - "These results suggest that theaflavin, theaflavin digallate, and (-)-epigallocatechin gallate inhibit tumor cell invasion by inhibiting type IV collagenases of the LL2-Lu3 cells." 09/01/1997 - "Theaflavin and theaflavin digallate also inhibited MMPs from the culture medium of these tumor cells, as did (-)-epigallocatechin gallate. "
5.	Infections 08/01/1991 - "Epigallocatechin gallate from green tea and theaflavin digallate from black tea inhibited infections of cultured rhesus monkey kidney MA 104 cells with rotaviruses and enteroviruses. "

Related Drugs and Biologics

1.	Tea
2.	epigallocatechin gallate (epigallocatechin-3-gallate)
3.	theaflavin
4.	Matrix Metalloproteinases (MMPs)
5.	Collagenases (Collagenase)
6.	Plasminogen Inactivators