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nitisinone (Orfadin)

used in treatment of hereditary tyrosinaemia type I
Also Known As:
Orfadin; 2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione; 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione; NTBC cpd
Networked: 159 relevant articles (16 outcomes, 27 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Ranganath, Lakshminarayan R: 18 articles (07/2022 - 01/2014)
2. Ranganath, L R: 16 articles (06/2022 - 01/2015)
3. Gallagher, James A: 16 articles (05/2022 - 01/2014)
4. Gallagher, J A: 15 articles (06/2022 - 01/2014)
5. Milan, A M: 13 articles (06/2022 - 01/2015)
6. Milan, Anna M: 12 articles (05/2022 - 01/2015)
7. Hughes, A T: 11 articles (06/2022 - 01/2018)
8. Khedr, M: 11 articles (06/2022 - 01/2018)
9. Hughes, Andrew T: 11 articles (01/2022 - 01/2015)
10. Davison, A S: 10 articles (06/2022 - 01/2018)

Related Diseases

1. Tyrosinemias (Tyrosinemia)
2. Alkaptonuria
3. Ochronosis
4. Hepatocellular Carcinoma (Hepatoma)
5. Disease Progression

Related Drugs and Biologics

1. Tyrosine (L-Tyrosine)
2. Phenylalanine (L-Phenylalanine)
3. Homogentisic Acid
4. Therapeutic Uses
5. Proteins (Proteins, Gene)
6. Enzymes
7. succinylacetone
8. Homogentisate 1,2-Dioxygenase (Homogentisate 1,2 Dioxygenase)
9. Acids
10. Dihydroxyphenylalanine (Dopa)

Related Therapies and Procedures

1. Therapeutics
2. Liver Transplantation
3. Protein-Restricted Diet (Diet, Protein Restricted)
4. Diet Therapy (Therapy, Diet)
5. Replacement Arthroplasty