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1,3,7,9-tetramethyluric acid (tetramethyluric acid)

RN from CHEMID

Also Known As:

tetramethyluric acid; theacrine; 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,3,7,9-tetramethyl-

Networked: 16 relevant articles (3 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Xanthines: 123
    - Uric Acid: 17354
      - 1,3,7,9-tetramethyluric acid: 16
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Xanthines: 123
        Uric Acid: 17354
        1,3,7,9-tetramethyluric acid: 16

Experts

1.	Jhuo, Cian-Fen: 2 articles (12/2021 - 11/2020)
2.	Tzen, Jason T C: 2 articles (12/2021 - 11/2020)
3.	He, Rong-Rong: 2 articles (10/2020 - 01/2018)
4.	Kurihara, Hiroshi: 2 articles (10/2020 - 01/2018)
5.	Li, Yi-Fang: 2 articles (10/2020 - 01/2018)
6.	Chen, Wen-Ying: 1 article (12/2021)
7.	Hsu, Yu-Yu: 1 article (12/2021)
8.	Gao, Ming: 1 article (12/2020)
9.	Huang, Qinwei: 1 article (12/2020)
10.	Huang, Zhiyuan: 1 article (12/2020)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 01/01/2018 - "The target of theacrine's activities on NAFLD is identified as SIRT3." 01/01/2018 - "Theacrine protects against nonalcoholic fatty liver disease by regulating acylcarnitine metabolism." 01/01/2018 - "Theacrine promotes acylcarnitine metabolism in NAFLD through the SIRT3/LCAD signaling pathway. " 01/01/2018 - "The aim of this study was to investigate the protective effects of theacrine, a rare purine alkaloid isolated from Camellia assamica var. kucha, against acylcarnitine metabolism disorder in NAFLD. "
2.	Liver Cirrhosis (Hepatic Cirrhosis) 09/01/2022 - "Theacrine ameliorates experimental liver fibrosis in rats by lowering cholesterol storage via activation of the Sirtuin 3-farnesoid X receptor signaling pathway."
3.	Infections 01/21/2023 - "Treatment with strictinin (100 μM), but not theacrine, completely eliminated MHV infection, as indicated by a pronounced reduction in plaque formation, nucleocapsid protein expression, and progeny production of MHV. "
4.	Fatigue 09/01/2017 - "In a double-blind, placebo-controlled study, theacrine increased energy, concentration, and mood, while reducing fatigue. " 01/01/2020 - "Present review examines the advances in the research on the health beneficial effects of theacrine, including antioxidant effect, anti-inflammatory effect, locomotor activation and reducing fatigue effects, improving cognitive effect, hypnotic effect, ameliorating lipid metabolism and inhibiting breast cancer cell metastasis effect. "
5.	Arthritis (Polyarthritis) 12/01/2020 - "The present study investigated the therapeutic effect of theacrine (TC) on arthritis and its mechanisms in Freund's incomplete adjuvant (FIA)-induced SD rats. "

Related Drugs and Biologics

1.	Alkaloids
2.	purine
3.	acylcarnitine
4.	strictinin
5.	Sirtuins
6.	Nucleocapsid Proteins
7.	Cholesterol
8.	Therapeutic Uses
9.	Sirtuin 3
10.	Caffeine (No Doz)