idrapril

structure given in first source

Also Known As:

2-(((2-(hydroxyamino)-2-oxoethyl)methylamino)carbonyl)cyclohexanecarboxylic acid; 2-((N-(2-hydroxyamino-2-oxoethyl)-N-methylamino)carbonyl)cyclohexane-1-carboxylic acid; LG 32001; LG-32001; Cyclohexanecarboxylic acid, 2-(((2-(hydroxyamino)-2-oxoethyl)methylamino)carbonyl)-, (1S-cis)-

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133

Related Diseases

1.	Essential Hypertension 01/01/1995 - "Idrapril calcium appears to be an effective ACE inhibitor in essential hypertension, with a hypotensive action for up to 24 h." 01/01/1995 - "Six untreated in-patients with essential hypertension were given single oral doses of the calcium salt of idrapril, idrapril calcium (200 mg) and placebo according to a double blind, randomised experimental design. "
2.	Ventricular Remodeling 03/01/1996 - "We evaluated the effects of a new angiotensin-converting enzyme (ACE) inhibitor (idrapril) in terms of hemodynamics and ventricular remodeling after myocardial infarction in rats. "
3.	Left Ventricular Dysfunction 03/01/1996 - "Effects of a new angiotensin-converting enzyme inhibitor (idrapril) in rats with left ventricular dysfunction after myocardial infarction."
4.	Myocardial Infarction 03/01/1996 - "Four-week treatment with idrapril initiated immediately after myocardial infarction reduced LVEDP and limited LV wall stress, a major prognostic factor for the progression toward chronic ventricular failure." 03/01/1996 - "Myocardial infarction was induced by left coronary artery ligation in the first two groups treated with either idrapril (300 mg kg-1 day-1) or vehicle for 4 weeks after myocardial infarction. " 03/01/1996 - "Effects of a new angiotensin-converting enzyme inhibitor (idrapril) in rats with left ventricular dysfunction after myocardial infarction." 03/01/1996 - "We evaluated the effects of a new angiotensin-converting enzyme (ACE) inhibitor (idrapril) in terms of hemodynamics and ventricular remodeling after myocardial infarction in rats. "
5.	Hypertension (High Blood Pressure) 07/01/1992 - "Idrapril (0.04-23 mumol/kg i.v.) lowered the blood pressure dose dependently, up to 20-35%, in different models of hypertension (sodium-depleted spontaneously hypertensive rat, two-kidney-one-clip renal hypertensive rat, and aortic-coarctated rat), its profile being similar to that of captopril in terms of potency and efficacy. "

Related Drugs and Biologics

1.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
2.	Calcium
3.	Sodium
4.	Salts
5.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
6.	Captopril (Capoten)
7.	Capsaicin (Zostrix)

Related Therapies and Procedures

1.	Surgical Instruments (Clip)
2.	Ligation