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betaIG-H3 protein (keratoepithelin)

binds to type I, II, and IV collagens; may play an important role in cell-collagen interactions; in cartilage, may be involved in endochondral bone formation; the gene was induced in a human adenocarcinoma cell line after treatment with TGF-beta; defects in TGGBI causes CORNEAL DYSTROPHIES, HEREDITARY; amino acid sequence in first source; RefSeq NM_009369 (mouse), NM_000358 (human); GenBank AB086407 (Zebrafish)
Also Known As:
keratoepithelin; BIGH3 protein; BIGH3 protein, human; Beta ig-h3 protein, zebrafish; Beta-ig protein, mouse; RGD-CAP protein; RGD-CAP protein, human; RGD-containing collagen associated protein; RGD-containing collagen associated protein, human; TGFBI protein; TGFBI protein, human; TGFBIp protein; Tgfbi protein, mouse; beta IG-H3 protein; big-h3 protein, mouse; bigh3 protein, zebrafish; kerato-epithelin; kerato-epithelin protein, human; kerato-epithilin; tgfbi protein, zebrafish; transforming growth factor, beta induced protein, mouse; transforming growth factor, beta-induced, 68kDa protein, human; transforming growth factor-beta induced protein
Networked: 109 relevant articles (0 outcomes, 8 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Enghild, Jan J: 8 articles (02/2016 - 08/2003)
2. Kim, Eung Kweon: 7 articles (03/2016 - 01/2008)
3. Klintworth, Gordon K: 6 articles (04/2014 - 08/2003)
4. Huang, Andrew J W: 5 articles (11/2012 - 01/2007)
5. Schorderet, Daniel F: 5 articles (06/2008 - 04/2005)
6. Karring, Henrik: 4 articles (04/2014 - 12/2004)
7. Runager, Kasper: 4 articles (04/2014 - 03/2009)
8. Hei, Tom K: 4 articles (01/2009 - 02/2006)
9. Kim, Tae-Im: 3 articles (03/2016 - 01/2008)
10. Poulsen, Ebbe Toftgaard: 3 articles (02/2016 - 01/2013)

Related Diseases

1. Hereditary Corneal Dystrophies
2. Corneal dystrophy Avellino type
3. Amyloid Plaque
4. Lattice corneal dystrophy type 1
5. Colorectal Neoplasms (Colorectal Cancer)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Biomarkers (Surrogate Marker)
3. Proteome
4. Mitomycin (Mitomycin-C)
5. Translationally-Controlled 1 Tumor Protein
6. Transforming Growth Factor beta (TGF-beta)
7. Codon (Codons)
8. Extracellular Matrix Proteins
9. Amyloid (Amyloid Fibrils)
10. Transforming Growth Factors (Transforming Growth Factor)

Related Therapies and Procedures

1. Laser In Situ Keratomileusis (LASIK)
2. Corneal Transplantation (Keratoplasty)
3. Drug Therapy (Chemotherapy)