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dfurin2

1680-residue protein from Drosophila melanogaster with multiple repeats of a cysteine motif; amino acid sequence given in first source

Also Known As:

dfurin 2

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Subtilisins: 71
        dfurin2: 1
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Subtilisins: 71
        dfurin2: 1

Related Diseases

1.

03/01/1995 - "The cleavage of pro-vWF by Dfurin2 shows that the previously reported lack of cleavage of the precursor of the beta A-chain of activin-A by Dfurin2 in this vaccinia expression system is substrate determined."
03/01/1995 - "In a vaccinia expression system, the endoprotease Dfurin2 not only cleaved wild-type precursor of von Willebrand factor (pro-vWF) with pro-region cleavage site R-S-K-R decreases, but also, although to a lesser extent, pro-vWF mutants in which the P2 (vWFK-2A) or P4 (vWFR-4A) basic residue with respect to the pro-region cleavage site had been mutated. "

Related Drugs and Biologics

1.	von Willebrand Factor
2.	activin A
3.	von Willebrand factor propolypeptide