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biotin-SS-methotrexate
structure given in first source; used to label folate transporter proteins for convenient purification
Also Known As:
biotin-SS-MTX
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
Biotin: 4061
biotin-SS-methotrexate: 1
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Pteridines: 147
Pterins: 160
Aminopterin: 248
Methotrexate: 24010
biotin-SS-methotrexate: 1
Enzymes and Coenzymes: 1
Coenzymes: 558
Biotin: 4061
biotin-SS-methotrexate: 1
Related Diseases
1.
Leukemia
01/01/1992 - "
Parental L1210 murine leukemia cells, which contain only the microM transporter (the reduced folate/MTX transport protein) were treated with the N-hydroxysulfosuccinimide ester of biotin-SS-MTX, and a detergent extract of the plasma membranes was exposed to streptavidin-agarose beads to adsorb the labeled protein.
"
Related Drugs and Biologics
1.
Proteins (Proteins, Gene)
2.
Folic Acid (Vitamin M)
3.
Esters
4.
Detergents (Detergent)
5.
Carrier Proteins (Binding Protein)
6.
streptavidin-agarose
7.
N-hydroxysulfosuccinimide